Multiple myeloma: The bone marrow microenvironment and its relation to treatment

Andrews, S. W.; Kabrah, S.; May, J. E.; Donaldson, C.; Morse, H. R.

doi:10.1080/09674845.2013.11669945

All Outputs (2)

Chemotherapy-induced cytotoxicity and genotoxicity to the bone marrow microenvironment (2013)
Journal Article

The bone marrow (BM) microenvironment is largely com- prised of mesenchymal stromal cells (MSCs) and is vital in supporting haematopoiesis. Limited studies have indicated that the BM microenvironment is damaged by chemotherapy; however the extent and... Read More about Chemotherapy-induced cytotoxicity and genotoxicity to the bone marrow microenvironment.

Multiple myeloma: The bone marrow microenvironment and its relation to treatment (2013)
Journal Article

Multiple myeloma is the most common haematological malignancy yet currently it remains incurable. For decades the mainstay in therapy has been non-targeted approaches including genotoxic agents and immunosuppressants. With myeloma predominantly affec... Read More about Multiple myeloma: The bone marrow microenvironment and its relation to treatment.