All Outputs (237)

A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study (2015)
Journal Article
Maskell, N. A., Kahan, B. C., Lyen, S. M., Sequeiros, I., Braybrooke, J. P., Morley, A. J., …Maskell, N. A. (2015). A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study. PLoS ONE, 10(3), https://doi.org/10.1371/journal.pone.0118569

© 2015 Clive et al. Introduction: Animal studies have shown Zoledronic Acid (ZA) may diminish pleural fluid accumulation and tumour bulk in malignant pleural disease (MPD). We performed a pilot study to evaluate its effects in humans. Methods: We und... Read More about A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study.

The effect of chemotherapy on health-related quality of life in mesothelioma: Results from the SWAMP trial (2015)
Journal Article
Arnold, D. T., Hooper, C. E., Morley, A., White, P., Lyburn, I. D., Searle, J., …Maskell, N. A. (2015). The effect of chemotherapy on health-related quality of life in mesothelioma: Results from the SWAMP trial. British Journal of Cancer, 112(7), 1183-1189. https://doi.org/10.1038/bjc.2015.77

© 2015 Cancer Research UK. All rights reserved. Background: The effect of chemotherapy on health-related quality of life (HRQoL) in malignant pleural mesothelioma (MPM) is poorly understood. Patient-individualised prognostication and prediction of tr... Read More about The effect of chemotherapy on health-related quality of life in mesothelioma: Results from the SWAMP trial.

Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study (2015)
Journal Article
White, P., Chambers, A. C., Bismohun, S. L., Davies, H., White, P., & Patil, A. V. (2015). Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study. International Journal of Surgery, 13, 207-210. https://doi.org/10.1016/j.ijsu.2014.11.041

© 2014 Surgical Associates Ltd. Appendicitis is a common clinical diagnosis aided by biochemical, haematological and radiological investigations. The role of some investigations, such as bilirubin, is controversial but could indicate complicated appe... Read More about Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study.

EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers (2015)
Journal Article
Kurian, K. M., DeSouza, R. M., Haynes, H. R., Faulkner, C., Palmer, A., Williams, H., …Kurian, K. M. (2015). EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers. British Journal of Neurosurgery, 29(1), 23-29. https://doi.org/10.3109/02688697.2014.950631

Copyright © 2014 The Neurosurgical Foundation. Introduction. EGFR and EGFRvIII analysis is of current interest because of new EGFRvIII vaccine trials opened in the UK. EGFR activation promotes cellular proliferation via activation of MAPK and PI3K-Ak... Read More about EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers.

Pleural irrigation trial (PIT): A randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection (2015)
Journal Article
Maskell, N. A., Zahan-Evans, N., Harvey, J. E., Medford, A. R., Clive, A. O., Edey, A. J., …Maskell, N. A. (2015). Pleural irrigation trial (PIT): A randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection. European Respiratory Journal, 46(2), 456-463. https://doi.org/10.1183/09031936.00147214

© ERS 2015. Pleural infection is increasing in incidence. Despite optimal medical management, up to 30% of patients will die or require surgery. Case reports suggest that irrigation of the pleural space with saline may be beneficial. A randomised con... Read More about Pleural irrigation trial (PIT): A randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection.

BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum (2015)
Journal Article
Faulkner, C., Ellis, H. P., Shaw, A., Penman, C., Palmer, A., Wragg, C., …Kurian, K. M. (2015). BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum. Journal of Neuropathology and Experimental Neurology, 74(9), 867-872. https://doi.org/10.1097/NEN.0000000000000226

Copyright © 2015 by the American Association of Neuropathologists, Inc. Pilocytic astrocytomas (PAs) are increasingly tested for KIAA1549-BRAF fusions. We used reverse transcription polymerase chain reaction for the 3 most common KIAA1549-BRAF fusion... Read More about BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum.

Women's views and experiences of antenatal enquiry for domestic abuse during pregnancy (2015)
Journal Article
Salmon, D., Baird, K., & White, P. (2015). Women's views and experiences of antenatal enquiry for domestic abuse during pregnancy. Health Expectations, 18(5), 867-878. https://doi.org/10.1111/hex.12060

© 2015 John Wiley & Sons Ltd. Objective: The aim of this study was to explore the acceptability of antenatal enquiry for domestic abuse from the perspective of women using maternity services. It also sought to understand the experiences of referral... Read More about Women's views and experiences of antenatal enquiry for domestic abuse during pregnancy.

Multimodal neurophysiological evaluation of primary progressive multiple sclerosis - An increasingly valid biomarker, with limits (2015)
Journal Article
Canham, L. J., Kane, N., Oware, A., Walsh, P., Blake, K., Inglis, K., …Cottrell, D. A. (2015). Multimodal neurophysiological evaluation of primary progressive multiple sclerosis - An increasingly valid biomarker, with limits. Multiple Sclerosis and Related Disorders, 4(6), 607-613. https://doi.org/10.1016/j.msard.2015.07.009

© 2015 Elsevier B.V. Background The promising utility of multi-modality evoked potential batteries to objectively measure multi-tract dysfunction has been evaluated by several groups using different methods. Objective To independently evaluate the us... Read More about Multimodal neurophysiological evaluation of primary progressive multiple sclerosis - An increasingly valid biomarker, with limits.

A pilot randomized controlled trial comparing bismuth iodine paraffin paste external ear pack and no ear pack after middle ear surgery (2015)
Journal Article
Nunez, D. A., Hajioff, D., Whitwell, R., Javed, F., Whitewell, R., Hakioff, D., …Nunez, D. A. (2015). A pilot randomized controlled trial comparing bismuth iodine paraffin paste external ear pack and no ear pack after middle ear surgery. European Archives of Oto-Rhino-Laryngology, 272(3), 543-550. https://doi.org/10.1007/s00405-013-2812-6

© 2013, The Author(s). To pilot a substantive randomized control trial comparing post-operative external ear canal pack with no ear pack after middle ear surgery, 32 adults undergoing primary posterior bony canal wall preserving middle ear surgery we... Read More about A pilot randomized controlled trial comparing bismuth iodine paraffin paste external ear pack and no ear pack after middle ear surgery.

Identification of the underlying factor structure of the Derriford Appearance Scale 24 (2014)
Report
Moss, T., Lawson, V., & White, P. (2014). Identification of the underlying factor structure of the Derriford Appearance Scale 24

Background. The Derriford Appearance Scale24 (DAS24) is a widely used measure of distress and dysfunction in relation to self-consciousness of appearance. It has been used in clinical and research settings, and translated into numerous European and A... Read More about Identification of the underlying factor structure of the Derriford Appearance Scale 24.

A systematic review of patient reported outcome measures used in child and adolescent burn care (2014)
Presentation / Conference
Griffiths, C., Rumsey, N., Armstrong-James, L., White, P., Pleat, J., & Harcourt, D. (2014, October). A systematic review of patient reported outcome measures used in child and adolescent burn care. Paper presented at 17th Congress of the International Society for Burn Injuries, Sydney, Australia

A systematic review of patient reported outcome measures (PROMs) used in child and adolescent burn research (2014)
Journal Article
Harcourt, D., Pleat, J., Rumsey, N., White, P., Armstrong-James, L., Griffiths, C., …Harcourt, D. (2015). A systematic review of patient reported outcome measures (PROMs) used in child and adolescent burn research. Burns, 41(2), 212-224. https://doi.org/10.1016/j.burns.2014.07.018

Crown Copyright © 2014 Published by Elsevier Ltd and ISBI. All rights reserved. Introduction: Patient reported outcome measures (PROMs) can identify important information about patient needs and therapeutic progress. The aim of this review was to ide... Read More about A systematic review of patient reported outcome measures (PROMs) used in child and adolescent burn research.

Interactive ant colony optimization (iACO) for early lifecycle software design (2014)
Journal Article
Simons, C., Smith, J., & White, P. (2014). Interactive ant colony optimization (iACO) for early lifecycle software design. Swarm Intelligence, 8(2), 139-157. https://doi.org/10.1007/s11721-014-0094-2

Finding good designs in the early stages of the software development lifecycle is a demanding multi-objective problem that is crucial to success. Previously, both interactive and non-interactive techniques based on evolutionary algorithms (EAs) have... Read More about Interactive ant colony optimization (iACO) for early lifecycle software design.

A systematic review of patient reported outcome measures (PROMs) for child and adolescent burn patients (2014)
Presentation / Conference
Griffiths, C., Rumsey, N., Armstrong-James, L., White, P., Pleat, J., & Harcourt, D. (2014, April). A systematic review of patient reported outcome measures (PROMs) for child and adolescent burn patients. Presented at British Burn Association Annual Meeting 2014, Anglia Ruskin University, Chelmsford, UK

Challenge and change: Police identity, morale and goodwill in an age of austerity (2014)
Report
Hoggett, J., Redford, P., Toher, D., & White, P. (2014). Challenge and change: Police identity, morale and goodwill in an age of austerity

One of the largest pieces of independent research on police attitudes in England and Wales. The research, led by Dr James Hoggett from UWE Bristol (the University of the West of England, Bristol), looked at police attitudes to current reform proposal... Read More about Challenge and change: Police identity, morale and goodwill in an age of austerity.

Salience and valence of appearance in a population with a visible difference of appearance: Direct and moderated relationships with self-consciousness, anxiety and depression (2014)
Journal Article
Moss, T. P., Lawson, V., White, P., Rumsey, N., Byron-Daniel, J., Charlton, R., …Walsh, E. (2014). Salience and valence of appearance in a population with a visible difference of appearance: Direct and moderated relationships with self-consciousness, anxiety and depression. PLoS ONE, 9(2), e88435. https://doi.org/10.1371/journal.pone.0088435

Psychometric measures of appearance salience and valence, CARSAL and CARVAL, have been previously demonstrated to be key factors underpinning appearance related self-consciousness and negative affect in the general population. However, the extent to... Read More about Salience and valence of appearance in a population with a visible difference of appearance: Direct and moderated relationships with self-consciousness, anxiety and depression.

The psychosocial impact of living with an ocular prosthesis (2014)
Journal Article
Lindenmeyer, A., Jenkinson, E., Harcourt, D., Moss, T., Clarke, S. A., Newell, R., …Newman, S. P. (2014). The psychosocial impact of living with an ocular prosthesis. Orbit, 33(1), 39-44. https://doi.org/10.3109/01676830.2013.851251

Objective: Many patients are satisfied with their ocular prosthesis, but some describe problems with social interactions, body image and self-esteem. Although both clinical practice and research suggest that the severity of a disfiguring condition do... Read More about The psychosocial impact of living with an ocular prosthesis.

The psychological well-being and appearance concerns of patients presenting with ptosis (2014)
Journal Article
White, P., Rumsey, N., Jenkinson, E., Richards, H. S., Jenkinson, E., Rumsey, N., …Harrad, R. A. (2014). The psychological well-being and appearance concerns of patients presenting with ptosis. Eye, 28(3), 296-302. https://doi.org/10.1038/eye.2013.264

PurposePtosis affects both the function and appearance of the eyes and face, because of drooping of the eyelids. Previous research has focused on functional impairment; however, similar appearance altering eye conditions have been demonstrated to hav... Read More about The psychological well-being and appearance concerns of patients presenting with ptosis.

Do long leg supine CT scanograms correlate with weight-bearing full-length radiographs to measure lower limb coronal alignment? (2014)
Journal Article
Porteous, A. J., White, P., Gbejuade, H. O., White, P., Hassaballa, M., Porteous, A. .. .., …Murray, J. R. (2014). Do long leg supine CT scanograms correlate with weight-bearing full-length radiographs to measure lower limb coronal alignment?. Knee, 21(2), 549-552. https://doi.org/10.1016/j.knee.2013.05.009

Introduction: The gold standard for measuring knee alignment is the lower limb mechanical axis (MA) using weight-bearing lower limb full-length x-ray (FLX). However, CT scanograms (CTS) are becoming increasingly popular in view of lower radiation exp... Read More about Do long leg supine CT scanograms correlate with weight-bearing full-length radiographs to measure lower limb coronal alignment?.

Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery (2014)
Journal Article
Harrison, O. J., Smart, N. J., White, P., Brigic, A., Carlisle, E. R., Allison, A. S., …Francis, N. K. (2014). Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery. Journal- Society of Laparoendoscopic Surgeons, 18(2), 265-272. https://doi.org/10.4293/108680813X13753907291918

Background and Objectives: Combining laparoscopy and enhanced recovery provides benefit to short-term outcomes after colorectal surgery. Advances in training and techniques have allowed surgeons to operate on cases that are technically challenging an... Read More about Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery.