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All Outputs (204)

Body confident coaching: A pilot randomized controlled trial evaluating the acceptability of a web-based body image intervention for coaches of adolescent girls (2023)
Journal Article

Coaches influence athletes’ body image, but often feel ill-equipped to address body image concerns and inadvertently perpetuate harmful body ideals. No evidence-based, empirically-tested body image intervention for coaches exists. This study evaluate... Read More about Body confident coaching: A pilot randomized controlled trial evaluating the acceptability of a web-based body image intervention for coaches of adolescent girls.

Insulin-like growth factor binding protein-2 and glucose-regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH-wildtype glioblastoma patients (2023)
Journal Article

Background: The overall survival of IDH-wildtype glioblastoma patients is poor despite best available treatments. There is an urgent need for new biomarkers to inform more precise disease stratification. Previous studies have identified insulin-like... Read More about Insulin-like growth factor binding protein-2 and glucose-regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH-wildtype glioblastoma patients.

Outcomes from a community speech and language therapy service treatment waiting list: The natural history of 525 children with identified speech and language needs (2023)
Journal Article

Abstract

Background
Understanding the natural history of developmental speech and language impairments can support the selection of children whose difficulties are persistent rather than transitory. It can also provide information against which... Read More about Outcomes from a community speech and language therapy service treatment waiting list: The natural history of 525 children with identified speech and language needs.

Outcomes from a community speech and language therapy service treatment waiting list: The natural history of 525 children with identified speech and language needs (2023)
Journal Article

Background: Understanding the natural history of developmental speech and language impairments can support the selection of children whose difficulties are persistent rather than transitory. It can also provide information against which the effective... Read More about Outcomes from a community speech and language therapy service treatment waiting list: The natural history of 525 children with identified speech and language needs.

The effect of isocaloric, energy-restrictive, KETOgenic diet on metabolism, inflammation, nutrition deficiencies and oxidative stress in women with overweight and obesity (KETO-MINOX): Study protocol (2023)
Journal Article

Obesity is considered one of the biggest health problems of the 21st century, becoming a worldwide epidemic, leading to the development of many diseases and increasing the risk of premature death. The first step in reducing body weight is a calorie-r... Read More about The effect of isocaloric, energy-restrictive, KETOgenic diet on metabolism, inflammation, nutrition deficiencies and oxidative stress in women with overweight and obesity (KETO-MINOX): Study protocol.

The randomised thoracoscopic talc poudrage+indwelling pleural catheters versus thoracoscopic talc poudrage only in malignant pleural effusion trial (TACTIC): Study protocol for a randomised controlled trial (2023)
Journal Article

INTRODUCTION: Malignant pleural effusion (MPE) is common, with 50 000 new cases per year in the UK. MPE causes disabling breathlessness and indicates advanced disease with a poor prognosis. Treatment approaches focus on symptom relief and optimising... Read More about The randomised thoracoscopic talc poudrage+indwelling pleural catheters versus thoracoscopic talc poudrage only in malignant pleural effusion trial (TACTIC): Study protocol for a randomised controlled trial.

Do congenital and acquired causes of visible difference predict distinct appearance-related psychosocial outcomes? (2023)
Journal Article

Having a visible difference caused by an appearance-altering condition or injury can impact psychosocial wellbeing. It remains unestablished whether the time at which a visible difference manifests, namely pre-memory (congenital) or later (acquired),... Read More about Do congenital and acquired causes of visible difference predict distinct appearance-related psychosocial outcomes?.

Evaluating the efficacy of a social media-based intervention (Warna-Warni Waktu) to improve body image among young Indonesian women: Parallel randomized controlled trial (2023)
Journal Article

BACKGROUND: Body dissatisfaction is a global issue, particularly among adolescent girls and young women. Effective body image interventions exist but face barriers to scaling up, particularly in lower- and middle-income countries, such as Indonesia,... Read More about Evaluating the efficacy of a social media-based intervention (Warna-Warni Waktu) to improve body image among young Indonesian women: Parallel randomized controlled trial.

Impact of procedure type on revisional surgery and secondary reconstruction after immediate breast reconstruction in a population-based cohort (2023)
Journal Article

Background: Women considering immediate breast reconstruction require high-quality information about the likely need for secondary reconstruction and the long-term risk of revisional surgery to make fully informed decisions about different reconstruc... Read More about Impact of procedure type on revisional surgery and secondary reconstruction after immediate breast reconstruction in a population-based cohort.

Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration (2023)
Journal Article

Introduction: Hospitalisations relating to acute respiratory deteriorations (ARD) in Interstitial Lung Disease (ILD) have poor outcomes. Factors predicting adverse outcomes are not fully understood and data addressing the use of illness severity scor... Read More about Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration.

Review of the partially overlapping samples framework: Paired observations and independent observations in two samples (2022)
Journal Article

A frequently asked question in quantitative research is how to compare two samples that include some combination of paired observations and unpaired observations. In our publications and R package, we refer to the scenario as ‘partially overlapping... Read More about Review of the partially overlapping samples framework: Paired observations and independent observations in two samples.

BRIVEST: A ‘real-world’ observational, single-centre study investigating the efficacy, safety and tolerability of Brivaracetam (2022)
Journal Article

Objective: Via measures of efficacy, tolerability, and safety, this open-label, single-center study assessed the overall effectiveness of Brivaracetam (BRV) for the treatment of epilepsy in the context of ‘real-world’ clinical practice. Methods: Unse... Read More about BRIVEST: A ‘real-world’ observational, single-centre study investigating the efficacy, safety and tolerability of Brivaracetam.

Acceptability of Lycra arm sleeve in people with sub-acute stroke: Patients', carers' and clinicians' perspectives (2022)
Journal Article

Background: Previous studies found that the Lycra sleeve has potential to reduce glenohumeral subluxation in people with stroke. The primary aim of this study was to explore the acceptability of the Lycra sleeve from patients’, carers’ and staff perc... Read More about Acceptability of Lycra arm sleeve in people with sub-acute stroke: Patients', carers' and clinicians' perspectives.

A comic-based body image intervention for adolescents in semi-rural Indian schools: Study protocol for a randomized controlled trial (2022)
Journal Article

Adolescents in India experience body dissatisfaction, however, empirically supported interventions are lacking. This paper describes the protocol for the development, acceptability testing, and cluster randomized controlled trial (RCT) of a six-sessi... Read More about A comic-based body image intervention for adolescents in semi-rural Indian schools: Study protocol for a randomized controlled trial.

A phase II trial of cemiplimab alone or in combination with standard of care chemotherapy in locally advanced or metastatic penile carcinoma (EPIC Trial) (2022)
Journal Article

TPS5094 Background: Penile cancer (PC) is rare but its incidence is increasing, with an increase of 21% over the last decade. The rarity of this cancer means a paucity of large prospective clinical trial data to guide the management of locally advanc... Read More about A phase II trial of cemiplimab alone or in combination with standard of care chemotherapy in locally advanced or metastatic penile carcinoma (EPIC Trial).