All Outputs (12)

Genomic profiling of IDH-wildtype and IDH-mutant initial and matched recurrent glioblastomas reveals clinically actionable mutations (e.g. BRCA1/2) and resistance signatures (2018)
Journal Article

Abstract: Background: Glioblastomas account for 90% of all adult brain tumours. Patient survival remains low because treatments are ineffective against this lethal disease. Understanding the genes and pathways altered in subtypes is necessary for th... Read More about Genomic profiling of IDH-wildtype and IDH-mutant initial and matched recurrent glioblastomas reveals clinically actionable mutations (e.g. BRCA1/2) and resistance signatures.

Methods for comparing the responses from a Likert question, with paired observations and independent observations in each of two samples (2018)
Journal Article

Assesses the robustness of the partially overlapping samples t-tests for ordinal samples. Introduces the Derrick-White Type I error robustness criteria.

Establishing the usefulness of the GO-QOL in a UK hospital-treated population with thyroid eye disease in the CIRTED trial (2018)
Journal Article

© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Thyroid eye disease (TED) is a potentially sight-threatening and cosmetically disfiguring condition arising in 25–50% of patients with Graves’ hyperthyroidism. CIRTED is the fir... Read More about Establishing the usefulness of the GO-QOL in a UK hospital-treated population with thyroid eye disease in the CIRTED trial.

Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS) (2018)
Journal Article

© 2018 The Author(s). Background: Nocturia is a common urinary symptom of multiple sclerosis (MS) which can affect quality of life (QoL) adversely. Melatonin is a hormone known to regulate circadian rhythm and reduce smooth muscle activity such as in... Read More about Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS).

Recurrence rates in primary spontaneous pneumothorax: A systematic review and meta-analysis (2018)
Journal Article

Copyright ©ERS 2018 Primary spontaneous pneumothorax (PSP) recurrence rates vary widely in the published literature, with limited data describing the factors that influence recurrence. The aims of this systematic review were to determine an estimati... Read More about Recurrence rates in primary spontaneous pneumothorax: A systematic review and meta-analysis.

Preschool children’s communication, motor and social development: Parents’ and educators’ concerns (2018)
Journal Article

© 2017, © 2017 The Speech Pathology Association of Australia Limited. Purpose: During early childhood, it is important to identify which children require intervention before they face the increased demands of school. This study aimed to: (1) compare... Read More about Preschool children’s communication, motor and social development: Parents’ and educators’ concerns.

Tests for equality of variances between two samples which contain both paired observations and independent observations (2018)
Journal Article

Tests for equality of variances between two samples which contain both paired observations and independent observations are explored using simulation. New solutions which make use of all of the available data are put forward. These new approaches are... Read More about Tests for equality of variances between two samples which contain both paired observations and independent observations.

Assessing vegetation response to soil moisture fluctuation under extreme drought using sentinel-2 (2018)
Journal Article

© 2018 by the authors. The aim of this study was to determine the extent to which Sentinel-2 Normalised Difference Vegetation Index (NDVI) reflects soil moisture conditions, and whether this product offers an improvement over Landsat-8. Based on drou... Read More about Assessing vegetation response to soil moisture fluctuation under extreme drought using sentinel-2.

Upfront docetaxel with androgen deprivation therapy in the elderly patient with metastatic hormone-naïve prostate cancer: Single institution experience (2018)
Journal Article

Upfront docetaxel with androgen deprivation therapy in the elderly patient with metastatic hormone-naïve prostate cancer: Single institution experience

Predictors of improved biochemical progression free survival for salvage prostate bed radiotherapy after radical prostatectomy (2018)
Journal Article

Predictors of improved biochemical progression free survival for salvage prostate bed radiotherapy after radical prostatectomy

Does personal experience of dementia change attitudes? The Bristol and South Gloucestershire survey of dementia attitudes (2018)
Journal Article

Background: it is unclear how attitudes towards people with dementia are formed and whether, for instance, increased contact with people with dementia, either through work or personal experience alters attitudes. This study used a validated questionn... Read More about Does personal experience of dementia change attitudes? The Bristol and South Gloucestershire survey of dementia attitudes.

18 F-Fluorodeoxyglucose PET/CT and dynamic contrast-enhanced MRI as imaging biomarkers in malignant pleural mesothelioma (2018)
Journal Article

© 2018 Wolters Kluwer Health, Inc. All rights reserved. Purpose The purpose of this study was to compare the use of fluorine-18-fluorodeoxyglucose (18 F-FDG) PET with computed tomography (CT) and dynamic contrast-enhanced (DCE) MRI to predict prognos... Read More about 18 F-Fluorodeoxyglucose PET/CT and dynamic contrast-enhanced MRI as imaging biomarkers in malignant pleural mesothelioma.