Skip to main content

Research Repository

Advanced Search

All Outputs (93)

The Pre-BRA (pre-pectoral Breast Reconstruction EvAluation) feasibility study: protocol for a mixed-methods IDEAL 2a/2b prospective cohort study to determine the safety and effectiveness of prepectoral implant-based breast reconstruction (2020)
Journal Article

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. INTRODUCTION: Implant-based breast reconstruction is the most commonly performed reconstructive technique worldwide. Subpectoral reconstruction with mesh is the... Read More about The Pre-BRA (pre-pectoral Breast Reconstruction EvAluation) feasibility study: protocol for a mixed-methods IDEAL 2a/2b prospective cohort study to determine the safety and effectiveness of prepectoral implant-based breast reconstruction.

Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches (2019)
Journal Article

© 2019 H. P. Ellis et al. Glioblastoma is the most common primary adult brain tumour, and despite optimal treatment, the median survival is 12-15 months. Patients with matched recurrent glioblastomas were investigated to try to find actionable mutati... Read More about Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches.

Experiential avoidance and cognitive fusion mediate the relationship between body evaluation and unhelpful body image coping strategies in individuals with visible differences (2019)
Journal Article

Psychological flexibility, the capacity to be open to any internal stimuli and act in accordance with valued ends, has been identified as an explanatory variable in how people cope with body concerns. The role of psychological flexibility is unexplor... Read More about Experiential avoidance and cognitive fusion mediate the relationship between body evaluation and unhelpful body image coping strategies in individuals with visible differences.

Characterising recovery from renal transplantation and live-related donation using cardiopulmonary exercise testing (2019)
Journal Article

Background: An association between end-stage renal failure and exercise intolerance exists. Whether live kidney donation impacts on exercise tolerance is unknown. Here recovery post renal transplant and donation using cardiopulmonary exercise testing... Read More about Characterising recovery from renal transplantation and live-related donation using cardiopulmonary exercise testing.

Parametric and non-parametric tests for the comparison of two samples which both include paired and unpaired observations (2019)
Journal Article

Samples that include both independent and paired observations cause a dilemma for researchers that covers the full breadth of empirical research. Parametric approaches for the comparison of two samples using all available observations are considered,... Read More about Parametric and non-parametric tests for the comparison of two samples which both include paired and unpaired observations.

Genomic profiling of IDH-wildtype and IDH-mutant initial and matched recurrent glioblastomas reveals clinically actionable mutations (e.g. BRCA1/2) and resistance signatures (2018)
Journal Article

Abstract: Background: Glioblastomas account for 90% of all adult brain tumours. Patient survival remains low because treatments are ineffective against this lethal disease. Understanding the genes and pathways altered in subtypes is necessary for th... Read More about Genomic profiling of IDH-wildtype and IDH-mutant initial and matched recurrent glioblastomas reveals clinically actionable mutations (e.g. BRCA1/2) and resistance signatures.

Establishing the usefulness of the GO-QOL in a UK hospital-treated population with thyroid eye disease in the CIRTED trial (2018)
Journal Article

© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Thyroid eye disease (TED) is a potentially sight-threatening and cosmetically disfiguring condition arising in 25–50% of patients with Graves’ hyperthyroidism. CIRTED is the fir... Read More about Establishing the usefulness of the GO-QOL in a UK hospital-treated population with thyroid eye disease in the CIRTED trial.

Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS) (2018)
Journal Article

© 2018 The Author(s). Background: Nocturia is a common urinary symptom of multiple sclerosis (MS) which can affect quality of life (QoL) adversely. Melatonin is a hormone known to regulate circadian rhythm and reduce smooth muscle activity such as in... Read More about Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS).

Preschool children’s communication, motor and social development: Parents’ and educators’ concerns (2018)
Journal Article

© 2017, © 2017 The Speech Pathology Association of Australia Limited. Purpose: During early childhood, it is important to identify which children require intervention before they face the increased demands of school. This study aimed to: (1) compare... Read More about Preschool children’s communication, motor and social development: Parents’ and educators’ concerns.

Tests for equality of variances between two samples which contain both paired observations and independent observations (2018)
Journal Article

Tests for equality of variances between two samples which contain both paired observations and independent observations are explored using simulation. New solutions which make use of all of the available data are put forward. These new approaches are... Read More about Tests for equality of variances between two samples which contain both paired observations and independent observations.

18 F-Fluorodeoxyglucose PET/CT and dynamic contrast-enhanced MRI as imaging biomarkers in malignant pleural mesothelioma (2018)
Journal Article

© 2018 Wolters Kluwer Health, Inc. All rights reserved. Purpose The purpose of this study was to compare the use of fluorine-18-fluorodeoxyglucose (18 F-FDG) PET with computed tomography (CT) and dynamic contrast-enhanced (DCE) MRI to predict prognos... Read More about 18 F-Fluorodeoxyglucose PET/CT and dynamic contrast-enhanced MRI as imaging biomarkers in malignant pleural mesothelioma.

A study protocol of the effectiveness of PEGASUS: A multi-centred study comparing an intervention to promote shared decision making about breast reconstruction with treatment as usual (2017)
Journal Article

© 2017 The Author(s). Background: Increasingly, women elect breast reconstruction after mastectomy. However, their expectations of surgery are often not met, and dissatisfaction with outcome and ongoing psychosocial concerns and distress are common.... Read More about A study protocol of the effectiveness of PEGASUS: A multi-centred study comparing an intervention to promote shared decision making about breast reconstruction with treatment as usual.

Test statistics for the comparison of means for two samples that include both paired and independent observations (2017)
Journal Article

©2017 JMASM, Inc. Standard approaches for analyzing the difference in two means, where partially overlapping samples are present, are less than desirable. Here are introduced two test statistics, making reference to the t-distribution. It is shown th... Read More about Test statistics for the comparison of means for two samples that include both paired and independent observations.

How to compare the means of two samples that include paired observations and independent observations: A companion to Derrick, Russ, Toher and White (2017) (2017)
Journal Article

Standard approaches for comparing the means of two samples, comprising both paired observations and independent observations, involve the discarding of valuable information. An alternative test which uses all of the available data, is the partially o... Read More about How to compare the means of two samples that include paired observations and independent observations: A companion to Derrick, Russ, Toher and White (2017).