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A randomized controlled trial of cognitive-behavior therapy plus bright light therapy for adolescent delayed sleep phase disorder

Gradisar, Michael; Dohnt, Hayley; Gardner, Greg; Paine, Sarah; Starkey, Karina; Menne, Annemarie; Slater, Amy; Wright, Helen; Hudson, Jennifer L.; Weaver, Edward; Trenowden, Sophie

Authors

Michael Gradisar

Hayley Dohnt

Greg Gardner

Karina Starkey

Annemarie Menne

Amy Slater Amy.Slater@uwe.ac.uk
Associate Professor in Centre for Appearance Research

Helen Wright

Jennifer L. Hudson

Edward Weaver

Sophie Trenowden



Abstract

Objective: To evaluate cognitive-behavior therapy plus bright light therapy (CBT plus BLT) for adolescents diagnosed with delayed sleep phase disorder (DSPD). Design: Randomized controlled trial of CBT plus BLT vs. waitlist (WL) control with comparisons at pre- and post-treatment. There was 6-month follow-up for the CBT plus BLT group only. Setting: Flinders University Child & Adolescent Sleep Clinic, Adelaide, South Australia. Patients: 49 adolescents (mean age 14.6 ± 1.0 y, 53% males) diagnosed with DSPD; mean chronicity 4 y 8 months; 16% not attending school. Eighteen percent of adolescents dropped out of the study (CBT plus BLT: N = 23 vs WL: N = 17). Interventions: CBT plus BLT consisted of 6 individual sessions, including morning bright light therapy to advance adolescents' circadian rhythms, and cognitive restructuring and sleep education to target associated insomnia and sleep hygiene. Measurements and Results: DSPD diagnosis was performed via a clinical interview and 7-day sleep diary. Measurements at each time-point included online sleep diaries and scales measuring sleepiness, fatigue, and depression symptoms. Compared to WL, moderate-to-large improvements (d = 0.65-1.24) were found at post-treatment for CBT plus BLT adolescents, including reduced sleep latency, earlier sleep onset and rise times, total sleep time (school nights), wake after sleep onset, sleepiness, and fatigue. At 6-month follow-up (N = 15), small-to-large improvements (d = 0.24-1.53) continued for CBT plus BLT adolescents, with effects found for all measures. Significantly fewer adolescents receiving CBT plus BLT met DPSD criteria at post-treatment (WL = 82% vs. CBT plus BLT = 13%, P < 0.0001), yet 13% still met DSPD criteria at the 6-month follow-up. Conclusions: CBT plus BLT for adolescent DSPD is effective for improving multiple sleep and daytime impairments in the immediate and long-term. Studies evaluating the treatment effectiveness of each treatment component are needed. Clinical Trial Information: Australia & New Zealand Trials Registry Number: ACTRN12610001041044.

Citation

Gradisar, M., Dohnt, H., Gardner, G., Paine, S., Starkey, K., Menne, A., …Trenowden, S. (2011). A randomized controlled trial of cognitive-behavior therapy plus bright light therapy for adolescent delayed sleep phase disorder. SLEEP, 34(12), 1671-1680. https://doi.org/10.5665/sleep.1432

Journal Article Type Article
Publication Date Dec 1, 2011
Journal Sleep
Print ISSN 0161-8105
Electronic ISSN 1550-9109
Publisher Oxford University Press (OUP)
Peer Reviewed Peer Reviewed
Volume 34
Issue 12
Pages 1671-1680
DOI https://doi.org/10.5665/sleep.1432
Keywords cognitive-behavior therapy, bright light therapy, adolescent, delayed sleep, disorder
Public URL https://uwe-repository.worktribe.com/output/968552
Publisher URL http://dx.doi.org/10.5665/sleep.1432