Daily reduction of oral malodor with the use of a sonic tongue brush combined with an antibacterial tongue spray in a randomized cross-over clinical investigation

Saad, Saliha; Gomez-Pereira, Paola; Hewett, Keith; Horstman, Peter; Patel, Jay; Greenman, John

Abstract

Abstract


The objective of this clinical investigation was to test the effectiveness on breath odor of a newly designed sonic tongue brush (TongueCare+, TC). It consists of a soft silicone brush optimally designed based on the tongue's anatomy to remove bacterial biofilm from the tongue's complex surface, and it is coupled with a sonic power toothbrush handle. TC was used in combination with an antibacterial tongue spray (BreathRx, BRx) containing 0.09% cetylpyridinium chloride and 0.7% zinc gluconate. A total of 21 participants with oral malodor exceeding the threshold for recognition took part in this cross-over clinical investigation, which consisted of a single use of four treatment arms with one week washout period in between. The treatments consisted of: (1) TC  +  BRx, (2) TC  +  water, (3) BRx and (4) water. Malodor levels and bacterial density were monitored up to 6 h by organoleptic scoring and selective plating, respectively. The organoleptic score and bacterial density were significantly lower after using TC  +  BRx compared to all alternative treatments at all time points. A significant decrease in both parameters was detected after a single use of TC  +  BRx, from levels characteristic of high oral malodor, to barely noticeable levels after treatment and this was maintained up to 6 h. Moreover, we identified a significant positive correlation between bacterial density and organoleptic score, confirming that bacterial tongue biofilm is the root cause of oral malodor in these subjects. The results of this clinical investigation demonstrated that the combined treatment of a sonic tongue brush with the antibacterial tongue spray is able to deliver more than 6 h of fresh breath following a single use. The clinical investigation was registered at the ISRCTN registry under study identification number ISRCTN38199132.

Citation

Saad, S., Gomez-Pereira, P., Hewett, K., Horstman, P., Patel, J., & Greenman, J. (2016). Daily reduction of oral malodor with the use of a sonic tongue brush combined with an antibacterial tongue spray in a randomized cross-over clinical investigation. Journal of Breath Research, 10(1), 13-16. https://doi.org/10.1088/1752-7155/10/1/016013

• Journal Article Type: Article
• Acceptance Date: Dec 23, 2015
• Online Publication Date: Feb 12, 2016
• Publication Date: Feb 12, 2016
• Deposit Date: Feb 18, 2016
• Publicly Available Date: Feb 18, 2016
• Journal: Journal of Breath Research
• Print ISSN: 1752-7155
• Electronic ISSN: 1752-7163
• Publisher: IOP Publishing
• Peer Reviewed: Peer Reviewed
• Volume: 10
• Issue: 1
• Article Number: 016013
• Pages: 13-16
• DOI: https://doi.org/10.1088/1752-7155/10/1/016013
• Keywords: malodor, halitosis, biofilms, organoleptic score, tongue cleaning, oral health
• Public URL: https://uwe-repository.worktribe.com/output/922961
• Publisher URL: http://iopscience.iop.org/article/10.1088/1752-7155/10/1/016013