Lawrence Bull Larry.Bull@uwe.ac.uk
School Director (Research & Enterprise) and Professor
On cellular darwinism: Mitochondria
Bull, Larry
Authors
Abstract
© 2016 Massachusetts Institute of Technology. The significant role of mitochondria within cells is becoming increasingly clear. This letter uses the NKCS model of coupled fitness landscapes to explore aspects of organelle-nucleus coevolution. The phenomenon of mitochondrial diversity is allowed to emerge under a simple intracellular evolutionary process, including varying the relative rate of evolution by the organelle. It is shown how the conditions for the maintenance of more than one genetic variant of mitochondria are similar to those previously suggested as needed for the original symbiotic origins of the relationship using the NKCS model.
Citation
Bull, L. (2016). On cellular darwinism: Mitochondria. Artificial Life, 22(1), 112-118. https://doi.org/10.1162/ARTL_a_00182
Journal Article Type | Article |
---|---|
Acceptance Date | Feb 17, 2016 |
Publication Date | Feb 1, 2016 |
Deposit Date | Jun 17, 2015 |
Publicly Available Date | May 17, 2016 |
Journal | Artificial Life |
Print ISSN | 1064-5462 |
Electronic ISSN | 1530-9185 |
Publisher | Massachusetts Institute of Technology Press (MIT Press) |
Peer Reviewed | Peer Reviewed |
Volume | 22 |
Issue | 1 |
Pages | 112-118 |
DOI | https://doi.org/10.1162/ARTL_a_00182 |
Keywords | evolution, mitochondria, cellular Darwinism |
Public URL | https://uwe-repository.worktribe.com/output/911075 |
Publisher URL | http://dx.doi.org/10.1162/ARTL_a_00182 |
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