© 2014 Massachusetts Institute of Technology. This article uses a recently presented abstract, tunable Boolean regulatory network model to further explore aspects of mobile DNA, such as transposons. The significant role of mobile DNA in the evolution of natural systems is becoming increasingly clear. This article shows how dynamically controlling network node connectivity and function via transposon-inspired mechanisms can be selected for to significant degrees under coupled regulatory network scenarios, including when such changes are heritable. Simple multicellular and coevolutionary versions of the model are considered.