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Fatigue in inflammatory arthritis

Dures, Emma; Cramp, Fiona; Hackett, Kate; Primdahl, Jette

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Emma Dures
Associate Professor in Rheumatology and Self-management

Fiona Cramp
Professor in Long Term Conditions

Kate Hackett

Jette Primdahl


Fatigue is highly prevalent in inflammatory arthritis, and people living with the symptom have described it as overwhelming and a challenge to manage. In this article, we explore the experience, impact and non-pharmacological management of fatigue from a multi-disciplinary perspective. We start by presenting qualitative evidence from people living with fatigue, including the physical, cognitive and emotional nature of the symptom and its impact on daily life. This is followed by discussion of current conceptual models of mechanisms and factors that may cause and maintain fatigue, within and between individuals. We then address the issue of fatigue measurement and modes of assessment, which is an integral aspect of management and evaluating support provision. This leads to a review of the research evidence for non-pharmacological interventions to reduce fatigue severity and impact. Finally, we consider implementation of this evidence in clinical practice and we introduce some key practical tools and techniques.


Dures, E., Cramp, F., Hackett, K., & Primdahl, J. (2020). Fatigue in inflammatory arthritis. Best Practice and Research: Clinical Rheumatology, 34(2),

Journal Article Type Article
Acceptance Date Mar 12, 2019
Online Publication Date May 27, 2020
Publication Date Apr 1, 2020
Deposit Date May 28, 2020
Publicly Available Date Apr 2, 2021
Journal Best Practice & Research Clinical Rheumatology
Print ISSN 1521-6942
Electronic ISSN 1532-1770
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 34
Issue 2
Article Number 101526
Keywords Rheumatology; Fatigue; Experiential nature; Multi-disciplinary; Non-pharmacological; Self-management
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