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Prevalence of Carbapenemase Producing Organisms in East London, UK.

Henderson, Jennifer; Ciesielczuk, Holly; Nelson, Shona


Jennifer Henderson

Holly Ciesielczuk


Carbapenemases are enzymes, produced by an array of common Gram-negative organisms, which hydrolyse the carbapenem antibiotics, conferring resistance [1]. The main protagonists are the “big five” carbapenemases, KPC, OXA-48, IMP, VIM and NDM, which have been reported across the UK.

Rates of carbapenemase producing organisms (CPOs) have risen over the past decade, with many hospitals in the UK reporting related outbreaks. However, these reports are often a result of reactive screening, outbreaks, inpatient surveillance and from diagnostic samples.
A point prevalence study (PPS) together with community screening was performed to determine the rate of carriage for our patient population. To date there have been no other community studies performed in the UK.

Presentation Conference Type Poster
Conference Name IBMS Congress 2019
Start Date Sep 22, 2019
End Date Sep 25, 2019
Deposit Date Oct 22, 2019
Public URL