Light-induced spiking response in proteinoid-actin-kombucha system

Mougkogiannis, Panagiotis; Nikolaidou, Anna; Adamatzky, Andrew

Abstract

This study examines the spiking response of a proteinoid–actin–kombucha system when exposed to varying frequency of yellow light pulses. The objective is to understand the frequency-dependent characteristics of this system's response and explore the possibility of using light pulses to regulate and manipulate how it functions. The kombucha samples, which contained proteinoid–actin complexes, were exposed to several stimulation conditions. These settings included no light (blank) and yellow light pulses at frequencies of 2 Hz, 4 Hz, 10 Hz, 20 Hz, and 100 Hz. The spiking response was analyzed in terms of potential (mV) over time (s), and the characteristics of the response, such as amplitude and period, were examined. The findings indicate that the spiking patterns and characteristics fluctuate according on the stimulation frequency, with higher frequencies generally leading to more distinct and numerous spikes compared to lower frequencies and the absence of stimulation. The skewness and kurtosis values of the potential data indicate different levels of asymmetry and tail tendency in the probability distributions, which further supports the fact that the response is based on frequency. The study emphasises the capacity to manipulate and regulate the functions of the proteinoid–actin–kombucha system using light pulses, hence creating opportunities for future usage in several domains, including biosensors and biocomputing.

• Journal Article Type: Article
• Acceptance Date: Oct 27, 2024
• Online Publication Date: Oct 28, 2024
• Deposit Date: Oct 31, 2024
• Publicly Available Date: Nov 1, 2024
• Journal: Materials Advances
• Print ISSN: 2633-5409
• Electronic ISSN: 2633-5409
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1039/d4ma00791c
• Public URL: https://uwe-repository.worktribe.com/output/13328424