Logical gates in ensembles of proteinoid microspheres

Mougkogiannis, Panagiotis; Adamatzky, Andrew

Abstract

Proteinoids are thermal proteins which swell into microspheres in aqueous solution. Ensembles of proteinoids produce electrical spiking activity similar to that of neurons. We introduce a novel method for implementing logical gates in the ensembles of proteinoid microspheres using chronoamperometry. Chronoamperometry is a technique that involves applying a voltage pulse to proteinoid microspheres and measuring their current response. We have observed that proteinoids exhibit distinct current patterns that align with various logical outputs. We identify four types of logical gates: AND, OR, XOR, and NAND. These gates are determined by the current response of proteinoid microspheres. Additionally, we demonstrate that proteinoid microspheres have the ability to modify their current response over time, which is influenced by their previous exposure to voltage. This indicates that they possess a capacity for learning and are capable of adapting to their environment. Our research showcases the ability of proteinoid microspheres to perform logical operations and computations through their inherent electrical properties.

• Journal Article Type: Article
• Acceptance Date: Sep 7, 2023
• Online Publication Date: Sep 18, 2023
• Publication Date: Sep 18, 2023
• Deposit Date: Sep 18, 2023
• Publicly Available Date: Sep 20, 2023
• Journal: PLoS ONE
• Electronic ISSN: 1932-6203
• Publisher: Public Library of Science
• Peer Reviewed: Peer Reviewed
• Volume: 18
• Issue: 9
• Article Number: e0289433
• DOI: https://doi.org/10.1371/journal.pone.0289433
• Public URL: https://uwe-repository.worktribe.com/output/11125526