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Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries

Ruddock, P. J.; Bird, David J.; McEvoy, J.; Peters, L. D.

Authors

P. J. Ruddock

David J. Bird

J. McEvoy

L. D. Peters



Abstract

A total of 94 European eels (Anguilla anguilla) were collected from five estuaries in the UK. The deconjugated metabolites of polycyclic aromatic hydrocarbons (PAHs) in the bile of the eels were separated using HPLC. Six PAH metabolites were identified: 1-hydroxy (1-OH) metabolites of phenanthrene, pyrene and chrysene; and the 1-OH, 3-OH and 7,8 dihydrodiol metabolites of benzo[a]pyrene (BaP). The mean concentration of the six metabolites was greatest in eels from the Tyne (49 μM) followed by the Wear (33 μM), Tees (19 μM), Thames (4 μM) and Severn (2 μM) estuaries. Although 1-OH pyrene was always the dominant compound, there were significant differences (P

Citation

Ruddock, P. J., Bird, D. J., McEvoy, J., & Peters, L. D. (2003). Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries. Science of the Total Environment, 301(1-3), 105-117. https://doi.org/10.1016/S0048-9697%2802%2900292-9

Journal Article Type Article
Publication Date Jan 1, 2003
Journal Science of the Total Environment
Print ISSN 0048-9697
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 301
Issue 1-3
Pages 105-117
DOI https://doi.org/10.1016/S0048-9697%2802%2900292-9
Keywords 1-Hydroxy pyrene, pollution monitoring, metabolite profiles, biomarker, bioavailability of PAH, sublethal effects
Public URL https://uwe-repository.worktribe.com/output/1072116
Publisher URL http://dx.doi.org/10.1016/S0048-9697(02)00292-9




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