Factors that influence cartilage implant integration during joint repair.

Al-obaid, A.; Quasnichka, Helen; Tarlton, J.; Kafienah, W.

Abstract

The low spontaneous healing capacity of articular cartilage, the avascular nature, and the acellularity of the interface of damaged cartilage, all these factors limit the integration between the implanted engineered cartilage and native articular cartilage. The disintegration remains an unsolved clinical problem as reported by many implantation
studies, regardless of the type of cells used in creating the implanted engineered cartilage. The purpose of this study was to investigate factors that influence implant integration with native cartilage.

• Journal Article Type: Article
• Online Publication Date: Dec 29, 2016
• Publication Date: Dec 29, 2016
• Deposit Date: Jun 28, 2023
• Journal: International Journal of Experimental Pathology
• Print ISSN: 0959-9673
• Electronic ISSN: 1365-2613
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 97
• Issue: 5
• Pages: A1-A19
• DOI: https://doi.org/10.1111/iep.12197
• Keywords: Cell Biology; Molecular Biology; Pathology and Forensic Medicine
• Public URL: https://uwe-repository.worktribe.com/output/10339203
• Publisher URL: https://onlinelibrary.wiley.com/doi/10.1111/iep.12197