Tiro Setati
Comparing closed-loop control of drug infusion using MPC and PID
Setati, Tiro; Perold, Willem; Fourie, Pieter; Withey, Daniel
Authors
Willem Perold
Pieter Fourie
Daniel Withey
Abstract
Continuous intravenous drug delivery can require careful dosage and the maintenance of consistent blood plasma concentration levels. Here, the closed-loop control of drug concentration in simulated patients’ bloodstreams was investigated. During the investigation, the closed-loop controller performance of a Proportional-Integral-Derivative (PID) and a Model Predictive Controller (MPC) were compared. From the simulation results, the MPC has shown to be a better controller because of its shorter settling time and smaller stepresponse overshoot, which are desirable in a clinical setting. However, the MPC has shown to be more resource-intensive on the controller system. Through the simulations conducted, it can therefore be concluded that a closed-loop controller containing an MPC control block adequately controls the drug infusion to a simulated patient.
Citation
Setati, T., Perold, W., Fourie, P., & Withey, D. (2022). Comparing closed-loop control of drug infusion using MPC and PID. In Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies - BIODEVICES (126-133). https://doi.org/10.5220/0010783700003123
Presentation Conference Type | Conference Paper (Published) |
---|---|
Conference Name | 15th International Conference on Biomedical Electronics and Devices |
Start Date | Feb 9, 2022 |
End Date | Feb 11, 2022 |
Acceptance Date | Nov 15, 2021 |
Publication Date | 2022 |
Deposit Date | Jan 12, 2023 |
Publicly Available Date | Jan 23, 2023 |
Pages | 126-133 |
Book Title | Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies - BIODEVICES |
DOI | https://doi.org/10.5220/0010783700003123 |
Keywords | Control Systems, Model-Predictive Controller (MPC), Proportional-Integral-Derivative (PID) Controller, Anesthesia, Intravenous Infusion |
Public URL | https://uwe-repository.worktribe.com/output/10339107 |
Publisher URL | https://www.scitepress.org/Link.aspx?doi=10.5220/0010783700003123 |
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http://creativecommons.org/licenses/by-nc-nd/4.0/
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