Modelling of the activation of G-protein coupled receptors: Drug free constitutive receptor activity
(2010)
Journal Article
G-protein coupled receptors (GPCRs) form a crucial component of approximately 80% of hormone pathways. In this paper, the most popular mechanism for activation of GPCRs-the shuttling mechanism-is modelled mathematically. An asymptotic analysis of thi... Read More about Modelling of the activation of G-protein coupled receptors: Drug free constitutive receptor activity.