Introduction Breast reconstruction (BR) is offered to improve quality of life for women with breast cancer undergoing mastectomy. As most women will be long-Term breast cancer survivors, high-quality information regarding the long-Term outcomes of di... Read More about Protocol for a national cohort study to explore the long-term clinical and patient-reported outcomes and cost-effectiveness of implant-based and autologous breast reconstruction after mastectomy for breast cancer: The Brighter Study.
Outputs (95)
Patient reported psychosocial functioning following successful ptosis surgery (2021)
Journal Article
Background: Ptosis may result in increased anxiety, appearance-related distress and social avoidance, and impacts visual function. Previous work demonstrates the benefits of ptosis surgery for health-related quality of life, but there is a paucity of... Read More about Patient reported psychosocial functioning following successful ptosis surgery.
Ambulatory management of secondary spontaneous pneumothorax: A randomised controlled trial (2021)
Journal Article
Secondary spontaneous pneumothorax (SSP) is traditionally managed with an intercostal chest tube attached to an underwater seal. We investigated whether use of a one-way flutter valve shortened patients' length of stay (LoS). This open-label randomis... Read More about Ambulatory management of secondary spontaneous pneumothorax: A randomised controlled trial.
“They were aware of who I was as a person”: Patients’ and health professionals’ experiences of using the PEGASUS intervention to facilitate decision-making around breast reconstruction (2021)
Journal Article
Objective: Many women choose to have breast reconstruction after mastectomy, however, decision-making can be difficult and expectations are often unmet. The PEGASUS intervention (Patient Expectations and Goals: Assisting Shared Understanding of Surge... Read More about “They were aware of who I was as a person”: Patients’ and health professionals’ experiences of using the PEGASUS intervention to facilitate decision-making around breast reconstruction.
Introduction: Approximately 40% of the 55,000 women diagnosed with breast cancer each year in the UK undergo mastectomy because they are considered unsuitable for standard breast conserving surgery (BCS) due to tumour size or multiple tumour foci. Ma... Read More about Protocol for a mixed-method study to inform the feasibility of undertaking a large-scale multicentre study comparing the clinical and patient-reported outcomes of oncoplastic breast conservation as an alternative to mastectomy with or without immediate breast reconstruction in women unsuitable for standard breast-conserving surgery (the ANTHEM Feasibility Study).
Acceptability and preliminary efficacy of a school-based body image intervention in urban India: A pilot randomised controlled trial (2021)
Journal Article
This pilot study evaluated the acceptability and preliminary efficacy of a culturally adapted school-based body image intervention, Dove Confident Me, for use in urban India. Two private schools in New Delhi were randomly assigned at the school level... Read More about Acceptability and preliminary efficacy of a school-based body image intervention in urban India: A pilot randomised controlled trial.
Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma (2021)
Journal Article
Introduction. Glioblastoma (GBM) is the most common primary adult brain tumour with a median overall survival (OS) of 12-15 months. Molecular characterization of multiple immunooncology targets in GBM may help target novel immunotherapeutic strategie... Read More about Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma.
Fixed bearing, all-polyethylene tibia, lateral unicompartmental arthroplasty – A final outcome study with up to 28 year follow-up of a single implant (2021)
Journal Article
Background: Lateral unicompartmental arthroplasty (UKA) constitutes only 5–10% of all unicompartmental replacements performed. Whilst the short and medium term benefits are well documented, there remains concern regarding the higher revision rate whe... Read More about Fixed bearing, all-polyethylene tibia, lateral unicompartmental arthroplasty – A final outcome study with up to 28 year follow-up of a single implant.
A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder (2021)
Journal Article
Introduction: Neoadjuvant cisplatin-based combination chemotherapy improves survival in muscle-invasive bladder cancer. However, response rates and survival remain suboptimal. We evaluated the efficacy, safety, and tolerability of cisplatin plus caba... Read More about A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder.
St Georg Sled medial unicompartmental arthroplasty: survivorship analysis and function at 20years follow up (2021)
Journal Article
Purpose: The peri-operative and short-term benefits of unicompartmental knee arthroplasty (UKA) are well supported in the literature. However, there remains concern regarding the higher revision rate when compared with total knee replacement. This ma... Read More about St Georg Sled medial unicompartmental arthroplasty: survivorship analysis and function at 20years follow up.