John Hancock's Outputs (175)

Nitric oxide synthesis and signalling in plants (2008)
Journal Article

As with all organisms, plants must respond to a plethora of external environmental cues. Individual plant cells must also perceive and respond to a wide range of internal signals. It is now well-accepted that nitric oxide (NO) is a component of the r... Read More about Nitric oxide synthesis and signalling in plants.

Nitric oxide evolution and perception (2008)
Presentation / Conference Contribution

Various experimental data indicate signalling roles for nitric oxide (NO) in processes such as xylogenesis, programmed cell death, pathogen defence, flowering, stomatal closure, and gravitropism. However, it still remains unclear how NO is synthesize... Read More about Nitric oxide evolution and perception.

Implications of dealing with airborne substances and reactive oxygen species: What mammalian lungs, animals, and plants have to say (2007)
Journal Article

A gas-exchange structure interacts with the environment and is constantly challenged by contaminants that may elicit defense responses, thus compromising its primary function. It is also exposed to high concentrations of O2 that can generate reactive... Read More about Implications of dealing with airborne substances and reactive oxygen species: What mammalian lungs, animals, and plants have to say.

Nitric oxide, stomatal closure and abiotic stress (2007)
Journal Article

Various data indicate that nitric oxide (NO) is an endogenous signal in plants that mediates responses to several stimuli. Experimental evidence in support of such signalling roles for NO has been obtained via the application of NO (usually in the fo... Read More about Nitric oxide, stomatal closure and abiotic stress.

Signaling on the stigma: Potential new roles for ROS and NO in plant cell signaling (2007)
Journal Article

Reactive oxygen species (ROS) and reactive nitrogen species, particularly NO, are key components of diverse signaling networks in animals and plants. We have recently shown that epidermal cells of stigmas from a range of different angiosperms accumul... Read More about Signaling on the stigma: Potential new roles for ROS and NO in plant cell signaling.

Biological free radicals and biomedical applications of EPR spectroscopy (2007)
Book Chapter

Nitric oxide evolution and perception (2007)
Journal Article

Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: Potential signalling crosstalk? (2006)
Journal Article

• Angiosperm stigmas exhibit high levels of peroxidase activity when receptive to pollen. To explore possible function(s) of this peroxidase activity we investigated amounts of reactive oxygen species (ROS), particularly hydrogen peroxide, in stigmas... Read More about Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: Potential signalling crosstalk?.

Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis (2006)
Journal Article

Ethylene is a plant hormone that regulates many aspects of growth and development. Despite the well-known association between ethylene and stress signalling, its effects on stomatal movements are largely unexplored. Here, genetic and physiological da... Read More about Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis.

Doing the unexpected: Proteins involved in hydrogen peroxide perception (2006)
Presentation / Conference Contribution

A look back at the early literature on reactive oxygen species (ROS) gives the impression that these small inorganic molecules had a singular defined role, that of host defence in mammalian systems. However, it is now known that their roles also incl... Read More about Doing the unexpected: Proteins involved in hydrogen peroxide perception.

The role of stigma peroxidases in flowering plants: Insights from further characterization of a stigma-specific peroxidase (SSP) from Senecio squalidus (Asteraceae) (2006)
Presentation / Conference Contribution

Angiosperm stigmas have long been known to exhibit high levels of peroxidase activity when they are mature and most receptive to pollen but the biological function of stigma peroxidases is not known. A novel stigma-specific class III peroxidase gene,... Read More about The role of stigma peroxidases in flowering plants: Insights from further characterization of a stigma-specific peroxidase (SSP) from Senecio squalidus (Asteraceae).

ABA-induced NO generation and stomatal closure in Arabidopsis are dependent on H2O2 synthesis (2006)
Journal Article

Nitric oxide (NO) and hydrogen peroxide (H2O2) are key signalling molecules produced in response to various stimuli and involved in a diverse range of plant signal transduction processes. Nitric oxide and H 2O2 have been identified as essential compo... Read More about ABA-induced NO generation and stomatal closure in Arabidopsis are dependent on H2O2 synthesis.

Oxygen metabolism coming up ROSes: A holistic view of the redox metabolism of plant cell (2006)
Journal Article

Preface to nitric oxide signalling: Plant growth and development (2006)
Journal Article

A role for ETR1 in hydrogen peroxide signaling in stomatal guard cells (2005)
Journal Article

Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis (2005)
Journal Article

Hydrogen peroxide (H2O2) is now recognised as a key signalling molecule in eukaryotes. In plants, H2O2 is involved in regulating stomatal closure, gravitropic responses, gene expression and programmed cell death. Although several kinases, such as oxi... Read More about Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis.

Reactive oxygen species as signalling molecules (2005)
Book Chapter

Recording forces exerted on the bowel wall during colonoscopy: in vitro evaluation. (2005)
Journal Article

A novel system for distributed force measurement between the bowel wall and the shaft of a colonoscope is presented. The system, based on the piezoresistive method, involves the integration of soft miniature transducers to a colonoscope to enable a w... Read More about Recording forces exerted on the bowel wall during colonoscopy: in vitro evaluation..

Role of xanthine oxidoreductase as an antimicrobial agent (2004)
Journal Article

DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines (2004)
Journal Article

This study used cDNA microarray technology to compare gene expression profiles in acute myeloblastic leukaemia (AML) with cDNA dot-blot and real time PCR analysis of cDNA transcripts to confirm array data. Patient AML marrow samples and AML cell line... Read More about DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines.