Paul White's Outputs (253)

The transcription factor PPARα is overexpressed and is associated with a favourable prognosis in IDH-wildtype primary glioblastoma (2016)
Journal Article

© 2016 John Wiley & Sons Ltd Aims: PPARα agonists are in current clinical use as hypolipidaemic agents and show significant antineoplastic effects in human glioblastoma models. To date however, the expression of PPARα in large-scale glioblastoma da... Read More about The transcription factor PPARα is overexpressed and is associated with a favourable prognosis in IDH-wildtype primary glioblastoma.

Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis (2016)
Journal Article

© 2016 John Wiley & Sons Ltd Background: Inflammatory bowel disease and irritable bowel syndrome may present in a similar manner. Measuring faecal calprotectin concentration is often recommended to rule out inflammatory bowel disease, however, ther... Read More about Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis.

Study protocol of the YP Face IT feasibility study: Comparing an online psychosocial intervention versus treatment as usual for adolescents distressed by appearance-altering conditions/injuries (2016)
Journal Article

© Published by the BMJ Publishing Group Limited. Introduction A significant number of adolescents suffer extensive and enduring difficulties such as social anxiety, body image dissatisfaction, low self-esteem and bullying as a result of conditions or... Read More about Study protocol of the YP Face IT feasibility study: Comparing an online psychosocial intervention versus treatment as usual for adolescents distressed by appearance-altering conditions/injuries.

Body Image in Primary Schools: A pilot evaluation of a primary school intervention program designed by teachers to improve children's body satisfaction (2016)
Journal Article

© 2016 Body Image in the Primary School (Hutchinson & Calland, 2011) is a body image curriculum that is widely available but has not yet been evaluated. This study evaluates a set of 6 of the 49 available lessons from this curriculum. Seventy-four gi... Read More about Body Image in Primary Schools: A pilot evaluation of a primary school intervention program designed by teachers to improve children's body satisfaction.

Defining recovery from Complex Regional Pain Syndrome (2016)
Presentation / Conference Contribution

AIM OF INVESTIGATION
The longevity and complexity of symptoms in persistent Complex Regional Pain Syndrome (CRPS) leads to problems in defining recovery and evaluating the efficacy of therapeutic interventions. Using a 2-Round Delphi-based process,... Read More about Defining recovery from Complex Regional Pain Syndrome.

A cross-sectional investigation of public attitudes toward dementia in Bristol and South Gloucestershire using the approaches to dementia questionnaire (2016)
Journal Article

© Copyright International Psychogeriatric Association 2016. Background: To date, surveys of attitudes toward dementia have largely been conducted using unvalidated materials or have focused on healthcare professionals supporting people affected by de... Read More about A cross-sectional investigation of public attitudes toward dementia in Bristol and South Gloucestershire using the approaches to dementia questionnaire.

The psychosocial experiences of breast cancer amongst Black, South Asian and White survivors: do differences exist between ethnic groups? (2016)
Journal Article

Copyright © 2016 John Wiley & Sons, Ltd. Background: Very little UK-based research has examined breast cancer-related experiences of Black and Minority Ethnic populations, and we do not know whether the psychosocial impact of diagnosis and treatmen... Read More about The psychosocial experiences of breast cancer amongst Black, South Asian and White survivors: do differences exist between ethnic groups?.

Understanding the physical and mental functioning of those with persistent and resolved Complex Regional Pain Syndrome to help inform treatment approaches (2016)
Presentation / Conference Contribution

Background
Pain is bio-psychosocial in nature. Recognising the inter-relationship of physical and psychological factors in Complex Regional Pain Syndrome (CRPS) has clinical implications for treating this often poorly understood chronic pain condit... Read More about Understanding the physical and mental functioning of those with persistent and resolved Complex Regional Pain Syndrome to help inform treatment approaches.

The acceptability of PEGASUS: An intervention to facilitate shared decision-making with women contemplating breast reconstruction (2016)
Journal Article

© 2015 The Author(s). Published by Taylor & Francis. Good practice guidelines recommend that women who undergo mastectomy are offered reconstructive surgery. However, many who choose this option report a degree of decisional regret and dissatisfact... Read More about The acceptability of PEGASUS: An intervention to facilitate shared decision-making with women contemplating breast reconstruction.

The use of a gas chromatography-sensor system combined with advanced statistical methods, towards the diagnosis of urological malignancies (2016)
Journal Article

© 2016 IOP Publishing Ltd. Prostate cancer is one of the most common cancers. Serum prostate-specific antigen (PSA) is used to aid the selection of men undergoing biopsies. Its use remains controversial. We propose a GC-sensor algorithm system for cl... Read More about The use of a gas chromatography-sensor system combined with advanced statistical methods, towards the diagnosis of urological malignancies.

Why Welch’s test is Type I error robust (2016)
Journal Article

The comparison of two means is one of the most commonly applied statistical procedures in psychology. The independent samples t-test corrected for unequal variances is commonly known as Welch’s test, and is widely considered to be a robust alternativ... Read More about Why Welch’s test is Type I error robust.

Urinary volatile organic compounds for the detection of prostate cancer (2015)
Journal Article

© 2015 Khalid et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cred... Read More about Urinary volatile organic compounds for the detection of prostate cancer.

Test statistics for comparing two proportions with partially overlapping samples (2015)
Journal Article

Standard tests for comparing two sample proportions of a dichotomous dependent variable where there is a combination of paired and unpaired samples are considered. Four new tests are introduced and compared against standard tests and an alternative p... Read More about Test statistics for comparing two proportions with partially overlapping samples.

The psychosocial impact of breast cancer diagnosis and treatment amongst Black, South Asian and White women: Do differences exist between ethnic groups? (2015)
Journal Article

Breast cancer is the most commonly diagnosed cancer in females, affecting women of all ethnic groups. Until now, very little research has captured the psychosocial impact of the disease amongst Black and Minority Ethnic (BME) women, and that which ha... Read More about The psychosocial impact of breast cancer diagnosis and treatment amongst Black, South Asian and White women: Do differences exist between ethnic groups?.

Cardiopulmonary reserve as determined by cardiopulmonary exercise testing correlates with length of stay and predicts complications after radical cystectomy (2015)
Journal Article

© 2014 The Authors. BJU International © 2014 BJU International. ObjectiveTo investigate whether poor preoperative cardiopulmonary reserve and comorbid state dictate high-risk status and can predict complications in patients undergoing radical cystect... Read More about Cardiopulmonary reserve as determined by cardiopulmonary exercise testing correlates with length of stay and predicts complications after radical cystectomy.

The South West Area Mesothelioma and Pemetrexed trial: A multicentre prospective observational study evaluating novel markers of chemotherapy response and prognostication (2015)
Journal Article

© 2015 Cancer Research UK. All rights reserved. Background: Robust markers that predict prognosis and detect early treatment response in malignant pleural mesothelioma (MPM) would enhance patient care. Methods: Consecutive patients with MPM who were... Read More about The South West Area Mesothelioma and Pemetrexed trial: A multicentre prospective observational study evaluating novel markers of chemotherapy response and prognostication.

A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study (2015)
Journal Article

© 2015 Clive et al. Introduction: Animal studies have shown Zoledronic Acid (ZA) may diminish pleural fluid accumulation and tumour bulk in malignant pleural disease (MPD). We performed a pilot study to evaluate its effects in humans. Methods: We und... Read More about A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study.

The effect of chemotherapy on health-related quality of life in mesothelioma: Results from the SWAMP trial (2015)
Journal Article

© 2015 Cancer Research UK. All rights reserved. Background: The effect of chemotherapy on health-related quality of life (HRQoL) in malignant pleural mesothelioma (MPM) is poorly understood. Patient-individualised prognostication and prediction of tr... Read More about The effect of chemotherapy on health-related quality of life in mesothelioma: Results from the SWAMP trial.

Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study (2015)
Journal Article

© 2014 Surgical Associates Ltd. Appendicitis is a common clinical diagnosis aided by biochemical, haematological and radiological investigations. The role of some investigations, such as bilirubin, is controversial but could indicate complicated appe... Read More about Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study.

EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers (2015)
Journal Article

Copyright © 2014 The Neurosurgical Foundation. Introduction. EGFR and EGFRvIII analysis is of current interest because of new EGFRvIII vaccine trials opened in the UK. EGFR activation promotes cellular proliferation via activation of MAPK and PI3K-Ak... Read More about EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers.