Dr Andrew Smith's Outputs (3)

Live birth rates and perinatal outcomes when all embryos are frozen compared with conventional fresh and frozen embryo transfer: a cohort study of 337,148 in vitro fertilisation cycles (2019)
Journal Article

BACKGROUND: It is not known whether segmentation of an in vitro fertilisation (IVF) cycle, with freezing of all embryos prior to transfer, increases the chance of a live birth after all embryos are transferred. METHODS: In a prospective study of UK H... Read More about Live birth rates and perinatal outcomes when all embryos are frozen compared with conventional fresh and frozen embryo transfer: a cohort study of 337,148 in vitro fertilisation cycles.

Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children (2019)
Journal Article

Objectives: Exposure to adversity has been linked to accelerated biological aging, which in turn has been shown to predict numerous physical and mental health problems. In recent years, measures of DNA methylation-based epigenetic age––known as “epig... Read More about Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children.

Sensitive periods for the effect of childhood adversity on DNA methylation: Results from a prospective, longitudinal study (2019)
Journal Article

Background: Exposure to "early life" adversity is known to predict DNA methylation (DNAm) patterns that may be related to psychiatric risk. However, few studies have investigated whether adversity has time-dependent effects based on the age at exposu... Read More about Sensitive periods for the effect of childhood adversity on DNA methylation: Results from a prospective, longitudinal study.