Maximum urethral closure pressure in women: Normative data and evaluation as a diagnostic test

Kapoor, Dharmesh S.; Housami, Fadi; Swithinbank, Lucy; White, Paul; Drake, Marcus

Abstract

Introduction and hypothesis: Our goal was to identify correlates of maximum urethral closure pressure (MUCP) and MUCP as a diagnostic test for stress urinary incontinence (SUI). Methods: This study was a retrospective review of women with non-neurological referrals for urinary incontinence between1995 and 2006. Results: We studied the characteristics of 8,644 women who underwent urodynamics for non-neurological referrals. Mean MUCP was 48 cm H2O in urodynamic stress incontinence (USI), 50 cm H2O in mixed urinary incontinence (MUI), 65 cm H2O in detrusor overactivity incontinence (DOI) and 67 cm H2O for continent women, Age and MUCP were negatively correlated in all groups. Multiple regression analysis showed lower levels of MUCP in women with USI who also had previous hysterectomy or anti-incontinence surgery or who were in an older age group. Previous anti-incontinence surgery and older age were risk factors for lower MUCP in women with MUI and DOI. Receiver operator curves did not show MUCP to have utility as a diagnostic test despite age and parity stratification. MUCP

• Journal Article Type: Review
• Publication Date: Jan 1, 2012
• Journal: International Urogynecology Journal
• Print ISSN: 0937-3462
• Electronic ISSN: 1433-3023
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 23
• Issue: 11
• Pages: 1613-1618
• DOI: https://doi.org/10.1007/s00192-012-1770-7
• Keywords: diagnostic test, maximum urethral closure, pressure, squeeze increments, urinary incontinence
• Public URL: https://uwe-repository.worktribe.com/output/954081
• Publisher URL: http://dx.doi.org/10.1007/s00192-012-1770-7