Alone NO Longer: Interactions of Nitric Oxide with Reactive Oxygen Species and Hydrogen Sulfide

Whiteman, Matthew; Hancock, John T.; Whiteman, Matt

Abstract

Nitric oxide (NO) is a hugely important signaling molecule in both animals and plants. In plants, it has been implicated in the control of a host of cellular and physiological events, from roots to leaves, from germination to senescence. It is known to be made by enzymes found in plants and to have downstream targets in cell signaling pathways. However, events leading to the initiation of the involvement of NO in signaling are often common to those which cause increases in reactive oxygen species and other reactive compounds such as hydrogen sulfide (H2S). The interaction of all these reactive compounds will be at several levels. They may react directly together given favourable conditions, with the potential to produce further signaling molecules. These mediators may interfere with each other's accumulation. They may control the enzymes that produce each other. Finally, they may compete for downstream targets, such as thiols on proteins. Therefore, NO signaling should be considered as part of an interactive web of reactive species, working together and competing with each other to lead to the final desirable outcome for the cell. Understanding this better will enable the development of chemicals which can manipulate such signaling, perhaps leading to control of plant diseases, better crops or better postharvest storage of plant materials. © 2016 Elsevier Ltd.

• Journal Article Type: Article
• Publication Date: Jan 1, 2016
• Journal: Advances in Botanical Research
• Print ISSN: 0065-2296
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 77
• Pages: 1-14
• Book Title: Advances in Botanical Research: Nitric Oxide and Signaling in Plants
• ISBN: 9780128011027
• DOI: https://doi.org/10.1016/bs.abr.2015.10.012
• Keywords: nitric oxide, reactive oxygen species, hydrogen sulfide, cell signalling, plant stress
• Public URL: https://uwe-repository.worktribe.com/output/919461
• Publisher URL: http://dx.doi.org/10.1016/bs.abr.2015.10.012