Skip to main content

Research Repository

Advanced Search

On cellular darwinism: Mitochondria

Bull, Larry

On cellular darwinism: Mitochondria Thumbnail


Authors

Lawrence Bull Larry.Bull@uwe.ac.uk
School Director (Research & Enterprise) and Professor



Abstract

© 2016 Massachusetts Institute of Technology. The significant role of mitochondria within cells is becoming increasingly clear. This letter uses the NKCS model of coupled fitness landscapes to explore aspects of organelle-nucleus coevolution. The phenomenon of mitochondrial diversity is allowed to emerge under a simple intracellular evolutionary process, including varying the relative rate of evolution by the organelle. It is shown how the conditions for the maintenance of more than one genetic variant of mitochondria are similar to those previously suggested as needed for the original symbiotic origins of the relationship using the NKCS model.

Journal Article Type Article
Acceptance Date Feb 17, 2016
Publication Date Feb 1, 2016
Deposit Date Jun 17, 2015
Publicly Available Date May 17, 2016
Journal Artificial Life
Print ISSN 1064-5462
Electronic ISSN 1530-9185
Publisher Massachusetts Institute of Technology Press (MIT Press)
Peer Reviewed Peer Reviewed
Volume 22
Issue 1
Pages 112-118
DOI https://doi.org/10.1162/ARTL_a_00182
Keywords evolution, mitochondria, cellular Darwinism
Public URL https://uwe-repository.worktribe.com/output/911075
Publisher URL http://dx.doi.org/10.1162/ARTL_a_00182
Contract Date Mar 11, 2016

Files






You might also like



Downloadable Citations