Median frequency and sum of amplitude changes in rising slope: Two potential non-invasive indicators for differentiating DU from BOO in males

Li, Rui; Gammie, Andrew; Zhu, Quanmin; Nibouche, Mokhtar

Abstract

It remains a challenge to non-invasively differentiate detrusor underactivity (DU) from bladder outlet obstruction (BOO) in males, and the gold standard is pressure flow studies, which is invasive, relatively expensive and may cause bleeding and infection. This novel study aims to non-invasively differentiate DU from BOO in males by analysing urine flow rate curves in the frequency domain. The hypothesis is that underactive patients may perform more abdominal straining than obstructed patients during micturition due to their underactive detrusor. Thus, it is possible to analyse the urine flow rate in frequency domain and derive non-invasive parameters for differentiating these two groups, as abdominal muscle strains in a different frequency range comparing with detrusor contraction.

• Journal Article Type: Article
• Acceptance Date: May 23, 2018
• Publication Date: Jul 5, 2018
• Deposit Date: Sep 17, 2018
• Publicly Available Date: Jul 5, 2019
• Journal: Neurology and Urodynamics
• Print ISSN: 0733-2467
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 37
• Issue: S5
• Pages: S248-S249
• DOI: https://doi.org/10.1002/nau.23760
• Keywords: frequency analysis of flow rate, non-invasive indicator
• Public URL: https://uwe-repository.worktribe.com/output/864818
• Publisher URL: https://doi.org/10.1002/nau.23760
• Additional Information: Additional Information : This is the peer reviewed version of the following article: [Li, R., Gammie, A., Zhu, Q. and Nibouche, M. (2018) Median frequency and sum of amplitude changes in rising slope: Two potential non-invasive indicators for differentiating DU from BOO in males. Neurology and Urodynamics, 37 (S5). S248-S249. ISSN 1520-6777], which has been published in final form at https://doi.org/10.1002/nau.23760. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
• Contract Date: Sep 17, 2018