Predicting the effects of low dose-rate ionizing radiation on redox potential in plant cells

Caplin, Nicol; Willey, Neil

Abstract

During exposure of cells to acute high dose-rate ionizing radiation (IR), oxidants from the radiolysis of water can overwhelm antioxidant systems. Protecting flora from the effects of IR released from a nuclear industry of increasing global significance and managing the growth of plants during space flight both necessitate estimating the effects of chronic low dose-rate exposure to IR. In contrast to effects at acute high-dose rates, under chronic low dose-rate exposure it is subtle, progressive, long-term effects on antioxidant systems that it is important to estimate. Here, we outline a method that combines biochemical measurement and mathematical modeling to predict the effects of chronic low dose-rate IR on redox potential in plant cells over time.

• Online Publication Date: May 31, 2019
• Publication Date: May 31, 2019
• Deposit Date: Nov 15, 2019
• Pages: 135-142
• Series Title: Methods in Molecular Biology
• Series Number: 1990
• Series ISSN: 1064-3745
• Book Title: Redox-Mediated Signal Transduction
• ISBN: 9781493994618
• DOI: https://doi.org/10.1007/978-1-4939-9463-2_11
• Public URL: https://uwe-repository.worktribe.com/output/4663264
• Publisher URL: https://doi.org/10.1007/978-1-4939-9463-2_11