Neural correlates of the inverse base rate effect

Inkster, A.B; Milton, F; Edmunds, C.E.R; Benattayallah, A; Wills, A.J

Abstract

The inverse base rate effect (IBRE) is a nonrational behavioral phenomenon in predictive learning. Canonically, participants learn that the AB stimulus compound leads to one outcome and that AC leads to another outcome, with AB being presented three times as often as AC. When subsequently presented with BC, the outcome associated with AC is preferentially selected, in opposition to the underlying base rates of the outcomes. The current leading explanation is based on error-driven learning. A key component of this account is prediction error, a concept previously linked to a number of brain areas including the anterior cingulate, the striatum, and the dorsolateral prefrontal cortex. The present work is the first fMRI study to directly examine the IBRE. Activations were noted in brain areas linked to prediction error, including the caudate body, the anterior cingulate, the ventromedial prefrontal cortex, and the right dorsolateral prefrontal cortex. Analyzing the difference in activations for singular key stimuli (B and C), as well as frequency matched controls, supports the predictions made by the error-driven learning account.

• Journal Article Type: Article
• Acceptance Date: Nov 15, 2021
• Online Publication Date: Nov 26, 2021
• Publication Date: Mar 31, 2022
• Deposit Date: Feb 20, 2025
• Publicly Available Date: Feb 27, 2025
• Journal: Human Brain Mapping
• Print ISSN: 1065-9471
• Electronic ISSN: 1097-0193
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 43
• Issue: 4
• Pages: 1370-1380
• DOI: https://doi.org/10.1002/hbm.25729
• Keywords: cognitive neuroscience, fMRI, human learning, inverse base rate effect, prediction error
• Public URL: https://uwe-repository.worktribe.com/output/13780806
• Publisher URL: http://researchspace.bathspa.ac.uk/15010/