Proteinoids–polyaniline interaction with stimulated neurons on living and plastic surfaces

Mougkogiannis, Panagiotis; Nikolaidou, Anna; Adamatzky, Andrew

Abstract

The integration of proteinoid-polyaniline (PANI) nanofibers with neuromorphic architectures shows potential for developing computer systems that are adaptable, energy-efficient, and have the capacity of tolerating faults. This work examines the capacity of proteinoid-PANI nanofibers to imitate different spiking patterns in stimulated Izhikevich neurons. The proteinoid-PANI nanofibers exhibit diverse spiking behaviors on different substrates, showcasing a broad range of control and programmability, as confirmed by experimental characterization and computational modeling. K-means clustering technique measures the extent and selectivity of the proteinoid-PANI spiking behavior in response to various stimuli and spiking patterns. The presence of strong positive correlations between membrane potential and time suggests that the system is capable of producing reliable and consistent electrical activity patterns. Proteinoid-PANI samples demonstrate enhanced stability and consistency in numerous spiking modes when compared to simulated input neurons. The results emphasize the capability of proteinoid-PANI nanofibers as a bioinspired substance for neuromorphic computing and open up possibilities for their incorporation into neuromorphic structures and bioinspired computer models.

• Journal Article Type: Article
• Acceptance Date: Sep 26, 2024
• Online Publication Date: Nov 5, 2024
• Deposit Date: Nov 6, 2024
• Publicly Available Date: Nov 19, 2024
• Journal: ACS Omega
• Electronic ISSN: 2470-1343
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 9
• Issue: 46
• Pages: 45789−45810
• DOI: https://doi.org/10.1021/acsomega.4c03546
• Public URL: https://uwe-repository.worktribe.com/output/13403360