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Outputs (28)

Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[ a]pyrene Toxicity in Human Normal and Cancer Cells That Express CYP1A1 (2018)
Journal Article

Copyright © 2018 American Chemical Society. Cytochrome P450 family 1 (CYP1) enzymes catalyze the metabolic activation of environmental procarcinogens such as benzo[a]pyrene, B[a]P, into carcinogens, which initiates the process of carcinogenesis. Thus... Read More about Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[ a]pyrene Toxicity in Human Normal and Cancer Cells That Express CYP1A1.

Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βa4 Peptide (2018)
Journal Article

© 2018 American Chemical Society. The overexpression of α-synuclein (α-syn) and its aggregation is the hallmark of Parkinson's disease. The α-syn aggregation results in the formation of Lewy bodies that causes neuronal cell death. Therefore, the smal... Read More about Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βa4 Peptide.

Industrial or traditional bamboo construction? Comparative life cycle assessment (LCA) of bamboo-based buildings (2018)
Journal Article

© 2018 by the authors. The past five decades have witnessed an unprecedented growth in population. This has led to an ever-growing housing demand. It has been proposed that the use of bio-based materials, and specifically bamboo, can help alleviate t... Read More about Industrial or traditional bamboo construction? Comparative life cycle assessment (LCA) of bamboo-based buildings.

Biotransformation, Using Recombinant CYP450-Expressing Baker's Yeast Cells, Identifies a Novel CYP2D6.10A122V Variant Which Is a Superior Metabolizer of Codeine to Morphine Than the Wild-Type Enzyme (2018)
Journal Article

© Copyright 2018 American Chemical Society. CYP2D6, a cytochrome P450 (CYP) enzyme, metabolizes codeine to morphine. Within the human body, 0-15% of codeine undergoes O-demethylation by CYP2D6 to form morphine, a far stronger analgesic than codeine.... Read More about Biotransformation, Using Recombinant CYP450-Expressing Baker's Yeast Cells, Identifies a Novel CYP2D6.10A122V Variant Which Is a Superior Metabolizer of Codeine to Morphine Than the Wild-Type Enzyme.

The many assumptions about self‐driving cars – Where are we heading and who is in the driving seat? (2018)
Presentation / Conference Contribution

Will our future be filled with self-driving cars? If so, when are they due to hit our streets, will they have steering wheels, and will people own them or hail them? There is, we suggest, an ‘emotive enthusiasm’ amongst policymakers and industry play... Read More about The many assumptions about self‐driving cars – Where are we heading and who is in the driving seat?.