Outputs (1475)

Towards the development of molecularly imprinted polymer based screen-printed sensors for metabolites of PAHs (2001)
Presentation / Conference Contribution

This paper describes the fabrication of a sensor for 1-hydroxypyrene (1-OHP) based on a screen-printed carbon electrode (SPCE) modified with a molecularly imprinted polymer (MIP); 1-OHP was chosen as a model metabolite of polyaromatic hydrocarbons (P... Read More about Towards the development of molecularly imprinted polymer based screen-printed sensors for metabolites of PAHs.

Hepatic metallothionein as a biomarker for metal contamination: Age effects and seasonal variation in European flounders (Pleuronectes flesus) from the Severn Estuary and Bristol Channel (2001)
Journal Article

Hepatic concentrations of metallothionein [MT] and three metals (Cu, Zn, Cd) were determined in 242 European flounders (Pleuronectes flesus) collected from power stations at Oldbury-upon-Severn and Hinkley Point, located in Severn Estuary and Bristol... Read More about Hepatic metallothionein as a biomarker for metal contamination: Age effects and seasonal variation in European flounders (Pleuronectes flesus) from the Severn Estuary and Bristol Channel.

Assessing the Potential of Phytoremediation at a Site in the U.K. Contaminated with 137Cs (2001)
Journal Article

Spinacia oleracea L. cv. 'Bloomsdale', Beta vulgaris L. cv. 'Flavescens', Brassica juncea L. 'OB825', and Helianthus annuus L. cv. 'Oranges and Lemons' were grown for 8 weeks at a site contaminated with 137Cs at Bradwell Nuclear Power Station, UK. Th... Read More about Assessing the Potential of Phytoremediation at a Site in the U.K. Contaminated with 137Cs.

Modulation of the fish immune system by hormones (2000)
Journal Article

Immune-neuroendocrine interactions in fish, as in mammals, have become a focus of considerable interest, with the modulation of immune responses by hormones receiving particular attention. Cortisol, growth hormone (GH), prolactin (PRL), reproductive... Read More about Modulation of the fish immune system by hormones.

4SR, a novel zinc-finger protein with SR-repeats, is expressed during early development of Xenopus (2000)
Journal Article

The protein C4SR contains two cysteine 4 (C 4) zinc-finger motifs at its amino terminus, a stretch of acidic residues in the middle and a series of serine-arginine (SR) repeats at its carboxyl terminus. A cDNA clone encoding the zinc-finger domain wa... Read More about 4SR, a novel zinc-finger protein with SR-repeats, is expressed during early development of Xenopus.

Supernatants from leucocytes treated with melanin-concentrating hormone (MCH) and α-melanocyte stimulating hormone (α-MSH) have a stimulatory effect on rainbow trout (Oncorhynchus mykiss) phagocytes in vitro (2000)
Journal Article

Melanin-concentrating hormone (MCH) and α-melanocyte stimulating hormone (α-MSH) are widespread vertebrate neuropeptides. In teleost fish the peptides are involved in the hormonal control of skin pigmentation, but they have also been shown to modulat... Read More about Supernatants from leucocytes treated with melanin-concentrating hormone (MCH) and α-melanocyte stimulating hormone (α-MSH) have a stimulatory effect on rainbow trout (Oncorhynchus mykiss) phagocytes in vitro.

A study of the effects of acid on the polymerisation of pyrrole, on the oxidative polymerisation of pyrrole and on polypyrrole (2000)
Journal Article

The polymer products arising from the hydrochloric acid treatment of aqueous pyrrole were shown to have spectroscopic data consistent with alternating pyrrole and pyrrolidine units with varying degrees of ring opening of the pyrrole units. The acid c... Read More about A study of the effects of acid on the polymerisation of pyrrole, on the oxidative polymerisation of pyrrole and on polypyrrole.

Development of a sensor system for the early detection of soft rot in stored potato tubers (2000)
Journal Article

A number of sensor types were fabricated and tested for their electrical resistance changes to compounds known to be evolved by potato tubers with soft rot caused by the bacterium Erwinia carotovora. On the basis of these tests, three sensors were se... Read More about Development of a sensor system for the early detection of soft rot in stored potato tubers.

A study of methods for evaluating the integrity of plate type heat exchangers used in the dairy industry (2000)
Journal Article

An overview of leak testing methods for heat exchangers is presented. The problems associated with the presence of residual liquid during testing were assessed as it was shown experimentally that complete drainage of plate type heat exchangers is ver... Read More about A study of methods for evaluating the integrity of plate type heat exchangers used in the dairy industry.

Air quality management: A temporal comparison of the extent of integration of local government departments (2000)
Book Chapter

Air quality management: stakeholder involvement in the local air quality management process (2000)
Book Chapter

Quantifying gene movement from oilseed rape to its wild relatives using remote sensing (2000)
Journal Article

The potential environmental risks due to gene flow from genetically modified (GM) crops into wild plant populations are currently of great concern. Of particular interest is gene flow from GM oilseed rape (Brassica napus) into its wild parental speci... Read More about Quantifying gene movement from oilseed rape to its wild relatives using remote sensing.

Cytochrome c release from isolated rat liver mitochondria can occur independently of outer-membrane rupture: possible role of contact sites (2000)
Journal Article

Percoll-purified rat liver mitochondria were shown to contain BAX dimer and rapidly (

Mitochondria and cell death (2000)
Presentation / Conference Contribution

Mitochondria play a central role in both apoptosis and necrosis through the opening of the mitochondrial permeability transition pore (MPTP). This is thought to be formed through a Ca2+-triggered conformational change of the adenine nucleotide transl... Read More about Mitochondria and cell death.

Mitochondria and cell death: a pore way to die? (2000)
Journal Article

Voltammetric behavior and trace determination of lead at a mercury-free screen-printed carbon electrode (2000)
Journal Article

Abstract Screen-printed carbon electrodes (SPCEs), without chemical modification, have been investigated as disposable sensors for the measurement of trace levels of Pb. Cyclic voltammetry was employed to elucidate the electrochemical behavior of Pb... Read More about Voltammetric behavior and trace determination of lead at a mercury-free screen-printed carbon electrode.

Voltammetric studies of Pb2+ at a modified screen-printed carbon electrode for trace determinations in natural waters by stripping voltammetry (2000)
Presentation / Conference Contribution

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain (2000)
Journal Article

Although metformin is widely used for the treatment of non-insulin-dependent diabetes, its mode of action remains unclear. Here we provide evidence that its primary site of action is through a direct inhibition of complex 1 of the respiratory chain.... Read More about Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain.

A direct regional scale estimate of transgene movement from genetically modified oilseed rape to its wild progenitors (2000)
Journal Article

One of the major environmental concerns over genetically modified (GM) crops relates to transgene movement into wild relatives. The pattern of hybridization ultimately affects the scale and rapidity of ecological change and the feasibility of contain... Read More about A direct regional scale estimate of transgene movement from genetically modified oilseed rape to its wild progenitors.

Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)+ ribonucleoprotein (1999)
Journal Article

The tumor suppressor gene WT1 encodes a zinc finger protein, which consists of four C-terminal C2-H2 zinc fingers of the Kruppel type, and at the N terminus a Q/P-rich trans-regulatory domain, both characteristic of transcription factors. However, re... Read More about Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)+ ribonucleoprotein.