Modulation of the fish immune system by hormones

Harris, James; Bird, David J.

Abstract

Immune-neuroendocrine interactions in fish, as in mammals, have become a focus of considerable interest, with the modulation of immune responses by hormones receiving particular attention. Cortisol, growth hormone (GH), prolactin (PRL), reproductive hormones, melanin-concentrating hormone (MCH) and proopiomelanocortin (POMC)-derived peptides have all been shown to influence immune functions in a number of fish species. This review summarises the known effects of these hormones on the fish immune system, as well as the often complex interactions between different hormones. The possible implications for fish health, with respect to aquaculture and the changes in immunocompetence that take place during different stages in the fish life cycle are also discussed. © 2000 Elsevier Science B.V.

• Journal Article Type: Short Survey
• Publication Date: Dec 29, 2000
• Journal: Veterinary Immunology and Immunopathology
• Print ISSN: 0165-2427
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 77
• Issue: 3-4
• Pages: 163-176
• DOI: https://doi.org/10.1016/S0165-2427%2800%2900235-X
• Keywords: neuroendocrine system, fish immune system, hormones, stress, POMC
• Public URL: https://uwe-repository.worktribe.com/output/1092297
• Publisher URL: http://dx.doi.org/10.1016/S0165-2427(00)00235-X