Outputs (1695)

Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring (2023)
Journal Article

Modern computed tomography (CT) databases are becoming an accepted resource for the practice and development of identification methods in forensic anthropology. However, the utility of 3D models created using free and open-source visualization softwa... Read More about Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring.

Genotoxicity of cytokines at chemotherapy-induced 'storm' concentrations in a model of the human bone marrow (2023)
Journal Article

Donor cell leukaemia (DCL) is a complication of haematopoietic stem cell transplantation where donated cells become malignant within the patient's bone marrow. As DCL predominates as acute myeloid leukaemia, we hypothesized that the cytokine storm fo... Read More about Genotoxicity of cytokines at chemotherapy-induced 'storm' concentrations in a model of the human bone marrow.

HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings (2023)
Journal Article

Disinfection is a mainstay of infection prevention, the importance of which was highlighted throughout the SARS-CoV-2 pandemic. There is frequent misuse of terminology surrounding chlorine solutions in the literature. This leads not only to confusion... Read More about HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings.

Are protein cavities and pockets commonly used by redox active signalling molecules? (2023)
Journal Article

It has been well known for a long time that inert gases, such as xenon (Xe), have significant biological effects. As these atoms are extremely unlikely to partake in direct chemical reactions with biomolecules such as proteins, lipids, and nucleic ac... Read More about Are protein cavities and pockets commonly used by redox active signalling molecules?.

An N-cyanoamide derivative of lithocholic acid co-operates with lysophosphatidic acid to promote human osteoblast (MG63) differentiation (2023)
Journal Article

Less-calcaemic vitamin D receptor (VDR) agonists have the potential to promote osteoblast maturation in a bone regenerative setting. The emergence of lithocholic acid (LCA) as a bona fide VDR agonist holds promise as an adjunct for arthroplasty follo... Read More about An N-cyanoamide derivative of lithocholic acid co-operates with lysophosphatidic acid to promote human osteoblast (MG63) differentiation.

Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements (2023)
Presentation / Conference Contribution

Preventing infections in joint replacements is a major ongoing challenge, with limited effective clinical technologies currently available for uncemented knee and hip prostheses. This research aims to develop a coating for titanium implants, consisti... Read More about Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements.

The therapeutic potential of oxyhydrogen gas in oncology: A study on Epstein–Barr Virus-immortalised B-lymphoblastoid (TK6) cells (2023)
Journal Article

Cancer is a leading cause of mortality worldwide. B-cells are a keystone of the adaptive immune response and are essential for the presentation of tumor-associated antigens to various types of T-cells. Approximately 1.5% of global cancer cases, inclu... Read More about The therapeutic potential of oxyhydrogen gas in oncology: A study on Epstein–Barr Virus-immortalised B-lymphoblastoid (TK6) cells.

Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells (2023)
Journal Article

Colorectal cancer (CRC) is a significant global health burden with a rising incidence worldwide. Distinct bacterial populations are associated with CRC development and progression, and it is thought that the relationship between CRC and associated gu... Read More about Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells.

New applications of gas chromatography and gas chromatography-mass spectrometry for novel sample matrices in the forensic sciences: A literature review (2023)
Journal Article

The investigation of novel sample matrices in the forensic sciences offers several possible advantages, such as allowing for results to be obtained in cases where common sample types are absent. This review focuses on the application of gas chromatog... Read More about New applications of gas chromatography and gas chromatography-mass spectrometry for novel sample matrices in the forensic sciences: A literature review.

The effects of molecular hydrogen therapies on fertility (2023)
Journal Article

Human reproductive health is an integral part of personal well-being that can markedly impact upon individuals, couples, families and the wider society. It is estimated that infertility affects 13 to 15% of the world’s population and with parents oft... Read More about The effects of molecular hydrogen therapies on fertility.

Gamification in biomedical science education: The successful implementation of Resimion, a scenario-based learning tool (2023)
Journal Article

Introduction: Scenario-based learning and gamification have many advantages in comparison to traditional didactic teaching methods, including development of many higher-level skills such as analysis and evaluation. It is hoped that these simulations... Read More about Gamification in biomedical science education: The successful implementation of Resimion, a scenario-based learning tool.

Ternary nanocomposite potentiates the lysophosphatidic acid effect on human osteoblast (MG63) maturation (2023)
Journal Article

Aim: This study aimed to investigate the potential of ternary nanocomposite (TNC) to support MG63 osteoblast maturation to EB1089-(3S)1-fluoro-3-hydroxy-4-(oleoyloxy)butyl-1-phosphonate (FHBP) cotreatment. Materials & methods: Binary (P25/reduced gra... Read More about Ternary nanocomposite potentiates the lysophosphatidic acid effect on human osteoblast (MG63) maturation.

The value of twinned pollinator-pollen metabarcoding: Bumblebee pollination service is weakly partitioned within a UK grassland community (2023)
Journal Article

Predicting ecological impact of declining bumblebee (Bombus) populations requires better understanding of interactions between pollinator partitioning of floral resources and plant partitioning of pollinator resources. Here, we combine Cytochrome Oxi... Read More about The value of twinned pollinator-pollen metabarcoding: Bumblebee pollination service is weakly partitioned within a UK grassland community.

H2S priming and plant abiotic stress tolerance (2023)
Book Chapter

Hydrogen sulfide (H2S) is an emerging multitasking signaling molecule involved in plant responses to many abiotic stresses, promoting tolerance and growth under limiting conditions. There is experimental evidence of cross talk between H2S and nitric... Read More about H2S priming and plant abiotic stress tolerance.

Reactive oxygen, nitrogen, and sulfur species cellular crosstalk (2023)
Book Chapter

Accumulating data highlight the fact that nitric oxide (NO), hydrogen sulfide (H2S), and reactive oxygen species (ROS) act as intercellular key signaling molecules in plants. These molecules act in a well-orchestrated manner that regulates cells redo... Read More about Reactive oxygen, nitrogen, and sulfur species cellular crosstalk.

Bacteria associated with acute oak decline: Where did they come from? We know where they go (2023)
Journal Article

Acute oak decline is a high-impact disease causing necrotic lesions on the trunk, crown thinning and the eventual death of oak. Four bacterial species are associated with the lesions—Brenneria goodwinii, Gibbsiella quercinecans, Rahnella victoriana a... Read More about Bacteria associated with acute oak decline: Where did they come from? We know where they go.

Nationwide tracing of two top freshwater fish invaders in Greece using environmental DNA sampling (2023)
Journal Article

Alien fish invasions are causing devastating impacts on native freshwater fauna; thus, rigorous, non-invasive and cost-effective biomonitoring of lotic and lentic freshwaters to design and implement appropriate prevention and control measures is now... Read More about Nationwide tracing of two top freshwater fish invaders in Greece using environmental DNA sampling.

Determination of the relative sensitivity of polyaniline inks and films to deprotonation by ammonia using UV–Vis spectroscopy (2023)
Journal Article

The deprotonation behavior of conducting polymers such as polyaniline (PANI) is an important functional parameter in the design of novel printed electronic devices, particularly for sensors and energy storage. PANI can be fabricated into films from p... Read More about Determination of the relative sensitivity of polyaniline inks and films to deprotonation by ammonia using UV–Vis spectroscopy.

Molecular hydrogen as a beneficial postharvest treatment (2023)
Book Chapter

Molecular hydrogen (H2) has been shown to have significant effects in plants, especially during stress responses. H2 treatment can be used as a gas or as an H2-enriched solution, often termed hydrogen-rich water (HRW). Cellular effects of H2 are ofte... Read More about Molecular hydrogen as a beneficial postharvest treatment.

Written evidence from Dr Emmanuel Nsiah Amoako (UKR0065) (2023)
Preprint / Working Paper

This is a written response to the House of Lords' Industry and Regulators Committee's inquiry into UK regulators, with a focus on their roles, remit, independence, and accountability. This submission focused on the role of the Forensic Science Regula... Read More about Written evidence from Dr Emmanuel Nsiah Amoako (UKR0065).