Outputs (126)

Low light optical detection of whole-cell bioluminescent bacterial bioreporters for visualisation of surface decontamination using nonthermal plasma (2013)
Presentation / Conference Contribution

Introduction: Maintenance of a clean, uncontaminated healthcare environment is instrumental in the delivery of modern healthcare. Nonthermal plasma is a technology with potential applications for sterilisation and disinfection in biological and medi... Read More about Low light optical detection of whole-cell bioluminescent bacterial bioreporters for visualisation of surface decontamination using nonthermal plasma.

The importance of methane breath testing: A review (2013)
Journal Article

Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test is now a well established noninvasive test for assessi... Read More about The importance of methane breath testing: A review.

The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease (2013)
Journal Article

Currently, the diagnosis of bowel diseases such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) relies on invasive and expensive procedures. Identification of biomarker-based tests to aid diagnosis is an important area of resea... Read More about The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease.

Fecal microbiome and volatile organic compound metabolome in obese humans with nonalcoholic fatty liver disease (2013)
Journal Article

BACKGROUND & AIMS: The histopathology of nonalcoholic fatty liver disease (NAFLD) is similar to that of alcoholic liver disease. Colonic bacteria are a source of many metabolic products, including ethanol and other volatile organic compounds (VOC) th... Read More about Fecal microbiome and volatile organic compound metabolome in obese humans with nonalcoholic fatty liver disease.

An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS (2013)
Journal Article

Analysis of volatile organic compounds (VOCs) from saliva, to aid disease diagnoses, has received little attention. This work aims to address the paucity of information on saliva volatiles and includes a database of newly identified compounds whilst... Read More about An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS.

A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace (2013)
Journal Article

There is a need to reduce the number of cystoscopies on patients with haematuria. Presently there are no reliable biomarkers to screen for bladder cancer. In this paper, we evaluate a new simple in-house fabricated, GC-sensor device in the diagnosis... Read More about A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace.

The Development of Novel Fuel Dehydrating Icing Inhibitors (2013)
Journal Article

Dissolved water is a normal component of jet fuel which is vapourised during combustion; however, free water is a contaminant that can starve engines, freeze to form ice crystals capable of blocking fuel feeds, support microbial growth, and contribut... Read More about The Development of Novel Fuel Dehydrating Icing Inhibitors.

Daily reduction of oral malodor with the use of a sonic tongue brush combined with an antibacterial tongue spray in a randomized cross-over clinical investigation (2016)
Journal Article

Abstract The objective of this clinical investigation was to test the effectiveness on breath odor of a newly designed sonic tongue brush (TongueCare+, TC). It consists of a soft silicone brush optimally designed based on the tongue's anatomy t... Read More about Daily reduction of oral malodor with the use of a sonic tongue brush combined with an antibacterial tongue spray in a randomized cross-over clinical investigation.

Robust feature extraction from impedimetric signals using wavelet packet decomposition with application to cytotoxicity testing (2012)
Journal Article

Impedance-based cytotoxicity testing provides a simple, real-time and non-invasive assay technique that interferes minimally with cell morphology and function. In this study, impedimetric measurements of ECV304 cells with increasing concentrations of... Read More about Robust feature extraction from impedimetric signals using wavelet packet decomposition with application to cytotoxicity testing.

Data reconciliation in a smart home sensor network (2013)
Journal Article

This paper describes a data-driven approach to sensor data validation. The data originates from a network of sensors embedded in an indoor environment such as an office, home, factory, public mall or airport. Data analysis is performed to automatical... Read More about Data reconciliation in a smart home sensor network.

Detection of intracellular ara-C/ara-CTP following treatment with the new anti-leukemic drug elacytarabine using a bioluminescent bacterial biosensor (2013)
Presentation / Conference Contribution

Cytarabine (ara-C) is an analogue of deoxycytidine with an established role in treating AML. Cytarabine depends on the human equilibrative nucleoside transporter-1 (hENT-1) for cellular entry (1). Loss of hENT-1 function in vitro has been shown to re... Read More about Detection of intracellular ara-C/ara-CTP following treatment with the new anti-leukemic drug elacytarabine using a bioluminescent bacterial biosensor.

Ant algorithms for image feature extraction (2013)
Journal Article

This paper extends on previous work in applying an ant algorithm to image feature extraction, focusing on edge pattern extraction, as well as the broader study of self-organisation mechanisms in digital image environments. A novel method of distribut... Read More about Ant algorithms for image feature extraction.

Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles (2013)
Journal Article

Magnetic immunoassays have been shown to have similar detection limits to conventional immunoassays, with the advantage of reduced total assay time. The aim of this study was to demonstrate that an integrated lysis and measurement system could be use... Read More about Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles.

Volatiles from oral anaerobes confounding breath biomarker discovery (2013)
Journal Article

The levels of compounds in exhaled mouth air do not necessarily reflect levels in the systemic circulation as bacteria can bio-transform substrates to produce compounds within the mouth. This should be of concern to researchers measuring breath volat... Read More about Volatiles from oral anaerobes confounding breath biomarker discovery.

Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay (2013)
Journal Article

The main aim of this study was to develop a standardized experimental assay to enable differential antimicrobial comparisons of test biocidal aerosols. This study represents the first chlorine-matched comparative assessment of the antimicrobial activ... Read More about Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay.

An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome (2013)
Journal Article

Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to invasive investigations in order to rule out other diseases and reassure their patients. Volatile organic metabolites (VOMs) are emitted from feces; understanding... Read More about An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome.

Microfabricated glucose biosensor for culture welloperation (2013)
Journal Article

A water-based carbon screen-printing ink formulation, containing the redox mediator cobalt phthalocyanine (CoPC) and the enzyme glucose oxidase (GOx), was investigated for its suitability to fabricate glucose microbiosensors in a 96-well microplate f... Read More about Microfabricated glucose biosensor for culture welloperation.

The dual role of paramagnetic particles for integrated lysis and measurement in a rapid immunoassay for intracellular proteins (2013)
Journal Article

A novel, integrated lysis and immunoassay methodology and system for intracellular protein measurement are described. The method uses paramagnetic particles both as a lysis agent and assay label resulting in a rapid test requiring minimal operator in... Read More about The dual role of paramagnetic particles for integrated lysis and measurement in a rapid immunoassay for intracellular proteins.

Abstracts of the 17th International Symposium on Bioluminescence and Chemiluminescence, May 28th - June 2nd, 2012, Guelph, Ontario, Canada (ISBC 2012).
Presentation / Conference Contribution

Tackling ageing continence through theory, tools & technology (TACT3) (2012)
Journal Article

After dementia, nothing is more feared by older people than the loss of continence. It is often the reason many people enter care facilities and can contribute to the breakdown of caring relationships. This paper reports on a three-year research proj... Read More about Tackling ageing continence through theory, tools & technology (TACT3).