Outputs (9)

An evaluation of blood transfusion service in Saudi Arabia (2024)
Thesis

Background: Blood transfusion is needed to support the care given to many medical and surgical patients, and can reduce morbidity and mortality. The blood transfusion service (BTS) in the Kingdom of Saudi Arabia (KSA) is hospital-based. This study ai... Read More about An evaluation of blood transfusion service in Saudi Arabia.

Understanding the chemotherapy-induced bystander effect; an evaluation of the role of cytokine storm in an in-vitro model of the human bone marrow (2024)
Thesis

The phenomenon of donor cell leukaemia (DCL) occurs following haematopoietic stem cell transplantation (HSCT), but its aetiology is currently unknown. Previous work within the research group identified a chemotherapy-induced bystander effect (CIBE) i... Read More about Understanding the chemotherapy-induced bystander effect; an evaluation of the role of cytokine storm in an in-vitro model of the human bone marrow.

Metabolic reprogramming and the role of the BCAT protein - implications for type 2 diabetes and Alzheimer's disease (2023)
Thesis

Introduction: Oxidative stress and impaired homeostasis are key features of type 2 diabetes mellitus, which is comorbid with Alzheimer’s disease. Dysregulation of the branched-chain aminotransferase protein, which is overexpressed in AD, is suggested... Read More about Metabolic reprogramming and the role of the BCAT protein - implications for type 2 diabetes and Alzheimer's disease.

An analysis of the NHS Cord Blood Bank; Barriers to cord blood donation and quality parameters limiting storage (2022)
Thesis

The NHS Cord Bank was established in 1996 to build an inventory of altruistically donated cord blood units to provide equity of access to all patients eligible for a stem cell transplant. Fixed cord blood collection sites were selected in areas of hi... Read More about An analysis of the NHS Cord Blood Bank; Barriers to cord blood donation and quality parameters limiting storage.

How do illness perceptions influence the effectiveness of self-management in individuals living in Bermuda with type 2 diabetes? (2021)
Thesis

Diabetes is a chronic condition that occurs when blood glucose, or blood sugar, levels are too high in the body (NHS, 2016). Diabetes UK (2009) estimates that self-management is 95% of managing diabetes. Self-management refers to an individual’s abil... Read More about How do illness perceptions influence the effectiveness of self-management in individuals living in Bermuda with type 2 diabetes?.

Marker development for the traceability of certified sustainably produced cacao (Theobroma cacao) in the chocolate industry (2021)
Thesis

Theobroma cacao (cocoa) is one of the most studied commodities around the world and the source of one of the world’s most consumed and familiar products, chocolate. The multibillion-pound industry has changed to a higher demand for sustainably certif... Read More about Marker development for the traceability of certified sustainably produced cacao (Theobroma cacao) in the chocolate industry.

Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects (2021)
Thesis

Advances in modern chemotherapeutic regimens have led to an increase in the overall survival of leukaemia patients in recent years. However, haematopoietic stem cell transplantation (HSCT) remains the curative option for these patients. In HSCT, high... Read More about Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects.

Women’s experience of traumatic childbirth: An interpretative phenomenological analysis (2020)
Thesis

Background
It has long been recognised that women may experience trauma as part of the birth process. Up to half of women worldwide report their birth as traumatic, therefore further investigation is a priority. Previous research has focused on wome... Read More about Women’s experience of traumatic childbirth: An interpretative phenomenological analysis.

Fenofibrate toxicity and impact on clinical biomarkers in patients with dyslipidaemia (2020)
Thesis

Introduction and aims: Fenofibrate is the most widely used fibric acid derivative for managing mixed dyslipidaemia, characterised by elevated levels of cholesterol, triglycerides and LDL cholesterol and low levels of HDL cholesterol. Fenofibrate is a... Read More about Fenofibrate toxicity and impact on clinical biomarkers in patients with dyslipidaemia.