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Outputs (18)

Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study (2020)
Journal Article

Background:
No previous studies have validated current clinical practice guidelines for the management of non-blanching rashes in children who have received meningococcal B and C vaccinations. The aim of this study was to evaluate the performance o... Read More about Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study.

Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children (2020)
Journal Article

Background: The National Institute for Health and Care Excellence (NICE) have called for research into the role of biomarkers, and specifically procalcitonin (PCT), for the early diagnosis of serious bacterial infections (SBI) in children. The aim of... Read More about Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children.

Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial (2020)
Journal Article

Background Key challenges to the successful conduct of The Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children (EcLiPSE) trial were identified at the pre-trial stage. These included practitioner anxieties about condu... Read More about Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial.

Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials (2020)
Journal Article

Background: Alternatives to prospective informed consent enable the conduct of paediatric emergency and critical care trials. Research without prior consent (RWPC) involves practitioners approaching parents after an intervention has been given and se... Read More about Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials.

COVID-19 emergency response assessment study: a prospective longitudinal survey of frontline doctors in the UK and Ireland: study protocol (2020)
Journal Article

INTRODUCTION: The COVID-19 pandemic is putting an unprecedented strain on healthcare systems globally. The psychological impact on frontline doctors of dealing with the COVID-19 pandemic is currently unknown. This longitudinal professional survey aim... Read More about COVID-19 emergency response assessment study: a prospective longitudinal survey of frontline doctors in the UK and Ireland: study protocol.

Loop-mediated isothermal amplification for the early diagnosis of invasive meningococcal disease in children (2020)
Journal Article

Background Rapid molecular diagnostic testing has the potential to improve the early recognition of meningococcal disease (MD). The aim of this study was to report on the diagnostic test accuracy of point-of-care loop-mediated isothermal amplificatio... Read More about Loop-mediated isothermal amplification for the early diagnosis of invasive meningococcal disease in children.

Exposure and confidence with critical non-airway procedures: A global survey of paediatric emergency medicine physicians (2020)
Journal Article

Background:
Children rarely experience critical illness, resulting in low exposure of emergency physicians (EPs) to critical procedures. Our primary objective was to describe senior EP confidence, most recent performance and/or supervision of criti... Read More about Exposure and confidence with critical non-airway procedures: A global survey of paediatric emergency medicine physicians.

The effect of patient observation on cranial computed tomography rates in children with minor head trauma (2020)
Journal Article

Background
Management of children with minor blunt head trauma often includes a period of observation to determine the need for cranial computed tomography (CT). Our objective was to estimate the effect of planned observation on CT use for each Pedi... Read More about The effect of patient observation on cranial computed tomography rates in children with minor head trauma.

Acute severe paediatric asthma: Study protocol for the development of a core outcome set, a Pediatric Emergency Research Networks (PERN) study (2020)
Journal Article

Background
Acute severe childhood asthma is an infrequent, but potentially life-threatening emergency condition. There is a wide range of different approaches to this condition, with very little supporting evidence, leading to significant variation... Read More about Acute severe paediatric asthma: Study protocol for the development of a core outcome set, a Pediatric Emergency Research Networks (PERN) study.