All Outputs (1097)

Targeting the splice factor kinases SRPK1 and CLK1 in leukaemia (2021)
Thesis

This study was aimed at investigating the effect of inhibiting SRPK1 in leukaemic cells. It was also aimed at exploring the potential utility of combining conventional leukaemia chemotherapy (such as imatinib) with compounds that inhibit SRPK1.

SR... Read More about Targeting the splice factor kinases SRPK1 and CLK1 in leukaemia.

Counter-terrorism measures in the classroom: Exploring the perceptions and experiences of education professionals enacting the Prevent Duty in Bath and Bristol (2021)
Thesis

While most education professionals report their straightforward enactment of Prevent, a critical multilevel analysis of 17 interviews with education professionals in the Bath and Bristol areas of the UK data demonstrates however, that the policy is w... Read More about Counter-terrorism measures in the classroom: Exploring the perceptions and experiences of education professionals enacting the Prevent Duty in Bath and Bristol.

Noise and morphogenesis: Uncertainty, randomness and control (2021)
Thesis

This thesis presents a processual ontology of noise by virtue of which morphogenesis (in its most general understanding as the processes by which order/form is created) must be instantiated. Noise is here outlined as the far from equilibrium environm... Read More about Noise and morphogenesis: Uncertainty, randomness and control.

Capital structure and firm growth: The case of Vietnamese listed firms (2021)
Thesis

This thesis provides a wide range of research on capital structure within the context of Vietnamese listed firms through three specific empirical studies. The first study focuses on analysing the adjustment process of capital structure towards the ta... Read More about Capital structure and firm growth: The case of Vietnamese listed firms.

Lens-less capture and emerging moving imaging technologies: An investigation into the ways in which digital pinhole capture and advances in lens-less capture in imaging technologies may affect the form and content of moving images (2021)
Thesis

This thesis is a practice-led enquiry that investigates the creative potential of pinhole video, a new imaging technique which is undocumented elsewhere. Although fixed pinhole image capture has been possible since the advent of chemical photography... Read More about Lens-less capture and emerging moving imaging technologies: An investigation into the ways in which digital pinhole capture and advances in lens-less capture in imaging technologies may affect the form and content of moving images.

A generic provenance framework to document public policy making processes (2021)
Thesis

Public policies impact the day to day activities of individuals. Effective public policy outcomes result in general acceptance among the community. The transparency in policy making process and participation during policy creation holds significant p... Read More about A generic provenance framework to document public policy making processes.

Marker development for the traceability of certified sustainably produced cacao (Theobroma cacao) in the chocolate industry (2021)
Thesis

Theobroma cacao (cocoa) is one of the most studied commodities around the world and the source of one of the world’s most consumed and familiar products, chocolate. The multibillion-pound industry has changed to a higher demand for sustainably certif... Read More about Marker development for the traceability of certified sustainably produced cacao (Theobroma cacao) in the chocolate industry.

The role of earnings and its components in predicting future cash flows: Evidence from the MENA region firms (2021)
Thesis

This thesis aims to examine the role of current earnings and its components - cash flows and accruals- in predicting the one-year-ahead cash flows from operations (CFO) in the MENA region country firms for the sample period 2005 to 2018. In order to... Read More about The role of earnings and its components in predicting future cash flows: Evidence from the MENA region firms.

Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects (2021)
Thesis

Advances in modern chemotherapeutic regimens have led to an increase in the overall survival of leukaemia patients in recent years. However, haematopoietic stem cell transplantation (HSCT) remains the curative option for these patients. In HSCT, high... Read More about Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects.

Exploring men’s experiences of their female partner’s sexual pain: A qualitative thematic analysis study (2021)
Thesis

Aims
Female sexual pain occurs within a relational context, yet little is known about partners’ experiences This study adds to the very small literature exploring men’s experience of sexual pain within a different-sex relationship. I aimed to give v... Read More about Exploring men’s experiences of their female partner’s sexual pain: A qualitative thematic analysis study.

‘In my own comfort zone’: Client experiences of relational aspects of Skype therapy for alcohol problems (2021)
Thesis

Background: therapists and counsellors are increasingly using Skype or equivalent video-based applications to offer treatment in place of face-to-face delivery of talking therapies. In the alcohol treatment sector, this offers a range of potential be... Read More about ‘In my own comfort zone’: Client experiences of relational aspects of Skype therapy for alcohol problems.

Iranian immigrant women’s experiences of domestic violence: An interpretative phenomenological analysis (2021)
Thesis

Domestic violence is a major social health problem. Intimate partner violence is one of the most common forms of violence against women worldwide. Domestic violence against groups of immigrant women in heterosexual relationships has been explored; ho... Read More about Iranian immigrant women’s experiences of domestic violence: An interpretative phenomenological analysis.

Ethical implications of artificial expression of emotion by social robots in assistive contexts (2021)
Thesis

This research investigated whether Artificial Expression of Emotion (AEE) by a social robot can lead to emotional deception and emotional attachment. The use of AEE can be beneficial, as it may encourage engagement, and can help to build trust in the... Read More about Ethical implications of artificial expression of emotion by social robots in assistive contexts.

Financial intelligence units and the prevention of money laundering: A comparative analysis of financial intelligence units in the United Kingdom, Singapore and Thailand (2021)
Thesis

This thesis examines the implementation of the international Anti-Money Laundering (AML) standards regarding the role of Financial Intelligence Units (FIU) under the Financial Action Task Force (FATF) Recommendations. The main research questions focu... Read More about Financial intelligence units and the prevention of money laundering: A comparative analysis of financial intelligence units in the United Kingdom, Singapore and Thailand.

A critical analysis of the impact of inter-generational differences on the attitudes to lifestyle behavioural change among South Asian population in the UK (2021)
Thesis

Background
Evidence reports that people from a South Asian background experience a higher prevalence of chronic lifestyle diseases, such as diabetes, obesity and heart disease, with correspondingly higher risk of morbidity and mortality. People who... Read More about A critical analysis of the impact of inter-generational differences on the attitudes to lifestyle behavioural change among South Asian population in the UK.

Modelling the effects of fiscal policy choices on debt, crises and recovery for small open economies (2021)
Thesis

Crises have littered human history with serious consequences for both the country and its people. The 2008 Great Recession and Asian Financial Crisis are exemplars of such serious economic and social damage that took many years to recover. Debt defau... Read More about Modelling the effects of fiscal policy choices on debt, crises and recovery for small open economies.

Facilitating the design of data-informed andragogic tools to promote hypercognition for UK access to higher education learners (2021)
Thesis

Access to Higher Education courses in the UK serve the purpose of providing a route to Higher Education level study for those without the requisite qualifications to do so. However, students on these courses tend to be disproportionately from groups... Read More about Facilitating the design of data-informed andragogic tools to promote hypercognition for UK access to higher education learners.

The video game asset pipeline - A pattern approach to visualization (2021)
Thesis

Video games consist of virtual worlds modelled as an approximation of either a real or imaginary environment. The amount of content required to populate the environments for Triple-A (AAA) video games doubles every few years to satisfy the expectatio... Read More about The video game asset pipeline - A pattern approach to visualization.

Expert-informed design and automation of persuasive, socially assistive robots (2021)
Thesis

Socially assistive robots primarily provide useful functionality through their social interactions with user(s). An example application, used to ground work throughout this thesis, is using a social robot to guide users through exercise sessions. Ini... Read More about Expert-informed design and automation of persuasive, socially assistive robots.

“What makes a house a home?”: A theoretical model for the architectural design of homes based on human psychological needs to support and promote users’ psychological well-being (2021)
Thesis

The current PhD thesis investigates the relationship between the Architectural design of homes and inhabitants’ psychological well-being. Psychological wellbeing is understood to be achieved by addressing human psychological needs. In fact, while the... Read More about “What makes a house a home?”: A theoretical model for the architectural design of homes based on human psychological needs to support and promote users’ psychological well-being.