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All Outputs (383)

Conservative management versus invasive management of significant traumatic pneumothoraces in the emergency department (the CoMiTED trial): A study protocol for a randomised non-inferiority trial (2024)
Journal Article

Introduction: Traumatic pneumothoraces are present in one of five victims of severe trauma. Current guidelines advise chest drain insertion for most traumatic pneumothoraces, although very small pneumothoraces can be managed with observation at the t... Read More about Conservative management versus invasive management of significant traumatic pneumothoraces in the emergency department (the CoMiTED trial): A study protocol for a randomised non-inferiority trial.

Effects of nature-based mindfulness on pain and wellbeing for adults with persistent pain: A systematic literature review (2024)
Journal Article

Background: Persistent pain (PP) is a complex mechanism affecting 35% to 51.3% of adults in the United Kingdom and is associated with significant reductions in quality of life. Understanding of PP and how best to treat it has developed over the past... Read More about Effects of nature-based mindfulness on pain and wellbeing for adults with persistent pain: A systematic literature review.

Micromechanical modeling of longitudinal compression behavior and failure mechanism of unidirectional carbon fiber reinforced aluminum composites involving initial fiber misalignment (2024)
Journal Article

A micromechanical model with realistic initial fiber misalignment (IFM) was developed to simulate the longitudinal compression behavior of unidirectional carbon fiber/aluminum composites. The matrix and fiber were modeled using ductile damage law and... Read More about Micromechanical modeling of longitudinal compression behavior and failure mechanism of unidirectional carbon fiber reinforced aluminum composites involving initial fiber misalignment.

Evaluating the participation of junior members and patient and healthcare professionals representatives in EULAR task forces: Results from an international survey (2024)
Journal Article

Objective European Alliance of Associations for Rheumatology (EULAR) task forces (TF) requires participation of ≥2 junior members, a health professional in rheumatology (HPR) and two patient research partners for the development of recommendations o... Read More about Evaluating the participation of junior members and patient and healthcare professionals representatives in EULAR task forces: Results from an international survey.

SGIP1 binding to the α-helical H9 domain of cannabinoid receptor 1 promotes axonal surface expression (2024)
Journal Article

Endocannabinoid signalling mediated by cannabinoid receptor 1 (CB1R, also known as CNR1) is critical for homeostatic neuromodulation of both excitatory and inhibitory synapses. This requires highly polarised axonal surface expression of CB1R, but how... Read More about SGIP1 binding to the α-helical H9 domain of cannabinoid receptor 1 promotes axonal surface expression.

IL-6 knockdown in a model of the human bone marrow, abrogates DNA damage induction in bystander cells post-chemotherapy induced cytokine release syndrome (2024)
Journal Article

Following infection or exposure to therapeutic agents, an aggressive immune response may result, termed cytokine storm (CS) or cytokine release syndrome. Here the innate immune system becomes uncontrolled, leading to serious consequences including po... Read More about IL-6 knockdown in a model of the human bone marrow, abrogates DNA damage induction in bystander cells post-chemotherapy induced cytokine release syndrome.

Attenuated-total-reflection Fourier-transformed spectroscopy as a rapid tool to reveal the molecular structure of insect powders as ingredients for animal feeds (2024)
Journal Article

Unsustainable agriculture contributes to disastrous global effects – insect-based feed shows potential due to their sustainable, nutritional, and waste upcycling properties. Current EU legislation restricts insect-based meals to fish, pork, and poult... Read More about Attenuated-total-reflection Fourier-transformed spectroscopy as a rapid tool to reveal the molecular structure of insect powders as ingredients for animal feeds.

Effectiveness of infection prevention and control interventions in health care facilities in Africa: A systematic review (2024)
Journal Article

Background Healthcare associated infections (HAIs) are a major threat to patient safety and quality care. However, they are avoidable by implementing evidence-based infection prevention and control measures. This re... Read More about Effectiveness of infection prevention and control interventions in health care facilities in Africa: A systematic review.

Replication of a local record keeping method for collecting road crash data in low resource settings: lessons from Bangladesh and Nepal (2024)
Journal Article

Background. Police road crash and injury data in low- and middle-income countries are known to under-report crashes, fatalities and injuries, especially for vulnerable road users. Local record keepers, who are members of the public, can be engaged to... Read More about Replication of a local record keeping method for collecting road crash data in low resource settings: lessons from Bangladesh and Nepal.

Measuring the impacts of participatory citizen science: Lessons from the WeCount sustainable mobility project (2024)
Journal Article

WeCount was designed to empower citizens in five case studies across Europe to take a leading role in the production of data, evidence, knowledge and solutions for local sustainable mobility. This practice insight aims to explore the suitability and... Read More about Measuring the impacts of participatory citizen science: Lessons from the WeCount sustainable mobility project.

Awake craniotomy with English and British Sign Language mapping in a patient with a left temporal glioblastoma reveals discordant speech-sign language maps (2024)
Journal Article

The aim of this case study was to describe differences in English and British Sign Language (BSL) communication caused by a left temporal tumour resulting in discordant presentation of symptoms, intraoperative stimulation mapping during awake craniot... Read More about Awake craniotomy with English and British Sign Language mapping in a patient with a left temporal glioblastoma reveals discordant speech-sign language maps.

Understanding the impact of organisational and operational stressors on the mental health of police officers in Ireland (2024)
Journal Article

The mental health of police officers is a critical yet under-researched area. They face unique operational and organisational stressors, including exposure to violence and trauma, as well as bullying, managerial conflict, and a lack of support in the... Read More about Understanding the impact of organisational and operational stressors on the mental health of police officers in Ireland.

A symbolic defeat? Exploring symbolism and failure in the social reuse of confiscated mafia real estate in Italy (2024)
Journal Article

Italy’s pioneering anti-mafia legislation allows confiscated assets to be handed over to civil society groups. The ‘symbolic’ benefits of this approach are much lauded, but ill-defined. In the context of increasing global interest in the social reuse... Read More about A symbolic defeat? Exploring symbolism and failure in the social reuse of confiscated mafia real estate in Italy.