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All Outputs (622)

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells (2011)
Journal Article

Background: Cyclooxygenase-2 (COX-2) overexpression in colorectal cancer increases levels of its protumorigenic product prostaglandin E2 (PGE2). The recently identified colorectal tumour suppressor 15-prostaglandin dehydrogenase (15-PGDH) catalyses p... Read More about β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells.

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness (2011)
Journal Article

The use of nanoparticles in medicine is ever increasing, and it is important to understand their targeted and non-targeted effects. We have previously shown that nanoparticles can cause DNA damage to cells cultured below a cellular barrier without cr... Read More about Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.

Families created through surrogacy: Mother–child relationships and children's psychological adjustment at age 7 (2011)
Journal Article

Each year, an increasing number of children are born through surrogacy and thus lack a genetic and/or gestational link with their mother. This study examined the impact of surrogacy on mother-child relationships and children's psychological adjustmen... Read More about Families created through surrogacy: Mother–child relationships and children's psychological adjustment at age 7.

Developing the evidence base of patient and public involvement in health and social care research: The case for measuring impact (2011)
Journal Article

While patient and public involvement (PPI) in health and social care research has progressed successfully in the last decade, a range of difficulties with the evidence base exist, including poor understanding of the concept of impact, limited theoriz... Read More about Developing the evidence base of patient and public involvement in health and social care research: The case for measuring impact.

Equine road user safety: Public attitudes, understandings and beliefs from a qualitative study in the United Kingdom (2011)
Journal Article

Horse riders represent a significant group of vulnerable road user and are involved in a number of accidents and near misses on the road. Despite this horse riders have received little attention both in terms of academic research and transport policy... Read More about Equine road user safety: Public attitudes, understandings and beliefs from a qualitative study in the United Kingdom.

A national survey of GP and nurse attitudes and beliefs towards depression after myocardial infarction (2011)
Journal Article

Aim. To investigate primary care practitioner's attitudes to depression after myocardial infarction. Background. Depression after myocardial infarction affects almost half of all patients and has a considerable negative effect on recovery. Despite th... Read More about A national survey of GP and nurse attitudes and beliefs towards depression after myocardial infarction.

Macrobenthic assemblage structure in a cool-temperate intertidal dwarf eelgrass bed in comparison with those from lower latitudes (2011)
Journal Article

The evolution and ecology of latitudinal patterns in marine macrofaunal biodiversity and assemblage structure are contentious. With the aim of investigating the occurrence of such patterns in intertidal dwarf eelgrass beds (Nanozosteraspp.), those at... Read More about Macrobenthic assemblage structure in a cool-temperate intertidal dwarf eelgrass bed in comparison with those from lower latitudes.