All Outputs (29)

The role of satellite image-processing for national-scale estimates of gene flow from genetically modified crops: Rapeseed in the UK as a model (2004)
Journal Article

1. There is concern over the possibility of unwanted environmental change following transgene movement from genetically modified (GM) rapeseed Brassica napus to its wild and weedy relatives. 2. The aim of this research was to develop a remote sensing... Read More about The role of satellite image-processing for national-scale estimates of gene flow from genetically modified crops: Rapeseed in the UK as a model.

The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone (2004)
Journal Article

Functional analysis of the pig cytochrome P4502E1 (CYP2E1) promoter identified two major activating elements. One corresponded to the hepatic nuclear factor 1 (HNF-1) consensus binding sequence at nucleotides -128/-98 and the other was located in the... Read More about The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone.

p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer (2004)
Journal Article

Deregulated tumour expression of p16INK4a has previously been described in association with clinical progression in sporadic colorectal cancer patients (CRC). Furthermore, p16INK4a promoter hypermethylation leading to gene silencing has been shown to... Read More about p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer.

Role of xanthine oxidoreductase as an antimicrobial agent (2004)
Journal Article

Fundamental subchondral bone changes in spontaneous knee osteoarthritis (2004)
Journal Article

Osteoarthritis has an unknown aetiology, and tissue samples from early stage human osteoarthritis tissue cannot be reliably obtained. Therefore understanding the development of OA relies on using animal models: such as the spontaneous changes seen in... Read More about Fundamental subchondral bone changes in spontaneous knee osteoarthritis.

DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines (2004)
Journal Article

This study used cDNA microarray technology to compare gene expression profiles in acute myeloblastic leukaemia (AML) with cDNA dot-blot and real time PCR analysis of cDNA transcripts to confirm array data. Patient AML marrow samples and AML cell line... Read More about DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines.

Penetrative convection induced by the absorption of radiation with a nonlinear internal heat source (2004)
Journal Article

A model for convection induced by the selective absorption of radiation in a fluid layer is investigated. The concentration based internal heat source is modelled quadratically. A linear analysis and conditional nonlinear analysis are performed. Due... Read More about Penetrative convection induced by the absorption of radiation with a nonlinear internal heat source.

Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme (2004)
Journal Article

The redox-active dithiol/disulfide C315-Xaa-Xaa-C318 center has been implicated in the regulation of the human mitochondrial branched chain aminotransferase isozyme (hBCATm) [Conway, M. E., Yennawar, N., Wallin, R., Poole, L. B., and Hutson, S. M. (2... Read More about Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme.

Effect of buffer on peak shape of peptides in reversed-phase high performance liquid chromatography (2004)
Journal Article

The effect of changing the buffer at constant low pH in the mobile phase is investigated with respect to the separation of a mixture of basic peptides. Considerably worse peak shapes, leading to poorer resolution of complex peptide mixtures, were obt... Read More about Effect of buffer on peak shape of peptides in reversed-phase high performance liquid chromatography.

Doubling the estimate of invertebrate biomass in a rainforest canopy (2004)
Journal Article

Forest canopies represent the functional interface between 90% of the Earth's terrestrial biomass and the atmosphere and include some of the most threatened of all terrestrial ecosystems. However, we lack even a basic understanding of how the biomass... Read More about Doubling the estimate of invertebrate biomass in a rainforest canopy.

Experimental implementation of mobile robot taxis with onboard Belousov-Zhabotinsky chemical medium (2004)
Journal Article

We discuss the first-ever experimental realization of the onboard excitable chemical controller for stimulus-guided navigation of mobile robots. We demonstrate that the Belousov-Zhabotinsky (BZ) reaction in the form of an onboard thin layer chemical... Read More about Experimental implementation of mobile robot taxis with onboard Belousov-Zhabotinsky chemical medium.

Some Recent Designs and Developments of Screen-Printed Carbon Electrochemical Sensors/Biosensors for Biomedical, Environmental, and Industrial Analyses (2004)
Journal Article

This review describes the design and fabrication of electrochemical sensors/biosensors based on screen-printing technology and their applications in pharmaceutical, biomedical, environmental, and industrial analyses. Specific emphasis is placed on na... Read More about Some Recent Designs and Developments of Screen-Printed Carbon Electrochemical Sensors/Biosensors for Biomedical, Environmental, and Industrial Analyses.

Reaction-diffusion navigation robot control: From chemical to VLSI analogic processors (2004)
Journal Article

We introduce a new methodology and experimental implementations for real-time wave-based robot navigation in a complex, dynamically changing environment. The main idea behind the approach is to consider the robot arena as an excitable medium, in whic... Read More about Reaction-diffusion navigation robot control: From chemical to VLSI analogic processors.

Conditional and unconditional nonlinear stability for convection induced by absorption of radiation in a porous medium (2004)
Journal Article

Convection induced by the selective absorption of radiation is investigated, for the case of an internal heat source that is modelled quadratically with respect to concentration. The growth rate for the linearised system is shown to be real, and a li... Read More about Conditional and unconditional nonlinear stability for convection induced by absorption of radiation in a porous medium.

Voltammetric, chromatographic and mass spectral elucidation of the redox reactions of 1-hydroxypyrene occurring at a screen-printed carbon electrode (2004)
Journal Article

The electrochemical oxidation of 1-hydroxypyrene (1-OHP) has been studied at a screen-printed carbon electrode (SPCE), by cyclic voltammetry and bulk electrolysis. Cyclic voltammograms exhibited two quasi-reversible pairs of peaks (designated 1a′/1c... Read More about Voltammetric, chromatographic and mass spectral elucidation of the redox reactions of 1-hydroxypyrene occurring at a screen-printed carbon electrode.

Use of External Magnetic Fields to Reduce Reaction Times in an Immunoassay Using Micrometer-Sized Paramagnetic Particles as Labels (Magnetoimmunoassay) (2004)
Journal Article

The paper presents a rapid immunoassay system capable of quantifying analyte in complex biological and environmental media. Antibody-coated micrometer-sized paramagnetic particles are used as labels in an assay in which they bind quantitatively with... Read More about Use of External Magnetic Fields to Reduce Reaction Times in an Immunoassay Using Micrometer-Sized Paramagnetic Particles as Labels (Magnetoimmunoassay).

Voronoi diagrams generated by regressing edges of precipitation fronts (2004)
Journal Article

The Voronoi diagram generated by regression edges of precipitation fronts was analyzed. In the reaction-diffusion system, one of the reagents penetrates into a gel by diffusion and forms a precipitate with the other reagent homogenized in the gel. It... Read More about Voronoi diagrams generated by regressing edges of precipitation fronts.

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation (2004)
Journal Article

Wt1 is a tumour suppressor gene, mutation of which is a cause of Wilms' tumour, a childhood renal nephroblastoma. Wt1 is expressed in a rich pattern during renal development suggesting that it acts at three stages: determination of the kidney area, t... Read More about Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.

New equations for redox and nano-signal transduction (2004)
Journal Article

Cells maintain redox potentials (Eh) in intracellular compartments, sometimes referred to as redox environments. These potentials are often very reducing, for example in the cytoplasm, but throughout the cell different potentials are maintained, comm... Read More about New equations for redox and nano-signal transduction.

Convection induced by the selective absorption of radiation for the Brinkman model (2004)
Journal Article

Convection induced by the selective absorption of radiation in a porous medium is studied analytically and numerically using the Brinkman model. Both linear instability analysis and nonlinear stability analysis are employed. The thresholds show excel... Read More about Convection induced by the selective absorption of radiation for the Brinkman model.