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All Outputs (16)

‘Dove Confident Me Indonesia: Single Session’: Study protocol for a randomised controlled trial to evaluate a school-based body image intervention among Indonesian adolescents (2021)
Journal Article

Background: Due to the prevalence and associated adverse health consequences of negative body image among adolescents globally, there is a need to develop acceptable, effective, and scalable interventions. School-based body image interventions delive... Read More about ‘Dove Confident Me Indonesia: Single Session’: Study protocol for a randomised controlled trial to evaluate a school-based body image intervention among Indonesian adolescents.

A multi-centred sequential trial comparing PEGASUS, an intervention to promote shared decision making about breast reconstruction with usual care (2021)
Journal Article

Decision making about breast reconstruction (BR) is complex. The Patients’ Expectations and Goals: Assisting Shared Understanding of Surgery (PEGASUS) intervention aims to support shared decision making by helping women and clinicians clarify and dis... Read More about A multi-centred sequential trial comparing PEGASUS, an intervention to promote shared decision making about breast reconstruction with usual care.

Testing the responsiveness of and defining MID (minimal important difference) values for the CARe Burn Scales: Patient-reported outcome measures (PROMs) to assess quality of life for children and young people affected by burn injuries, and their parents/caregivers (2021)
Journal Article

Background: The CARe Burn Scales are a portfolio of burn-specific PROMs for people affected by burns, including a Child Form (for children < 8 years (Parent-proxy)), a Young Person Form (for young people aged 8 -17 years), an Adult Form, and a Parent... Read More about Testing the responsiveness of and defining MID (minimal important difference) values for the CARe Burn Scales: Patient-reported outcome measures (PROMs) to assess quality of life for children and young people affected by burn injuries, and their parents/caregivers.

Ordinal Logistic Regression as an alternative analysis strategy for the comparison of two independent samples (2021)
Journal Article

The two group between subjects design is pervasive with analyses often performed using the Mann Whitney Rank Sum test or using the Welch variant of the t-test. Using simulation it is shown that a dummy variable ordinal logistic regression (OLR) mode... Read More about Ordinal Logistic Regression as an alternative analysis strategy for the comparison of two independent samples.

Application of a solid-phase microextraction-gas chromatography-mass spectrometry/metal oxide sensor system for detection of antibiotic susceptibility in urinary tract infection-causing Escherichia coli – A proof of principle study (2021)
Journal Article

Purpose: Antibiotic resistance is widespread throughout the world and represents a serious health concern. There is an urgent need for the development of novel tools for rapidly distinguishing antibiotic resistant bacteria from susceptible strains. P... Read More about Application of a solid-phase microextraction-gas chromatography-mass spectrometry/metal oxide sensor system for detection of antibiotic susceptibility in urinary tract infection-causing Escherichia coli – A proof of principle study.

Protocol for a national cohort study to explore the long-term clinical and patient-reported outcomes and cost-effectiveness of implant-based and autologous breast reconstruction after mastectomy for breast cancer: The Brighter Study (2021)
Journal Article

Introduction Breast reconstruction (BR) is offered to improve quality of life for women with breast cancer undergoing mastectomy. As most women will be long-Term breast cancer survivors, high-quality information regarding the long-Term outcomes of di... Read More about Protocol for a national cohort study to explore the long-term clinical and patient-reported outcomes and cost-effectiveness of implant-based and autologous breast reconstruction after mastectomy for breast cancer: The Brighter Study.

“They were aware of who I was as a person”: Patients’ and health professionals’ experiences of using the PEGASUS intervention to facilitate decision-making around breast reconstruction (2021)
Journal Article

Objective: Many women choose to have breast reconstruction after mastectomy, however, decision-making can be difficult and expectations are often unmet. The PEGASUS intervention (Patient Expectations and Goals: Assisting Shared Understanding of Surge... Read More about “They were aware of who I was as a person”: Patients’ and health professionals’ experiences of using the PEGASUS intervention to facilitate decision-making around breast reconstruction.

Protocol for a mixed-method study to inform the feasibility of undertaking a large-scale multicentre study comparing the clinical and patient-reported outcomes of oncoplastic breast conservation as an alternative to mastectomy with or without immediate breast reconstruction in women unsuitable for standard breast-conserving surgery (the ANTHEM Feasibility Study) (2021)
Journal Article

Introduction: Approximately 40% of the 55,000 women diagnosed with breast cancer each year in the UK undergo mastectomy because they are considered unsuitable for standard breast conserving surgery (BCS) due to tumour size or multiple tumour foci. Ma... Read More about Protocol for a mixed-method study to inform the feasibility of undertaking a large-scale multicentre study comparing the clinical and patient-reported outcomes of oncoplastic breast conservation as an alternative to mastectomy with or without immediate breast reconstruction in women unsuitable for standard breast-conserving surgery (the ANTHEM Feasibility Study).

Acceptability and preliminary efficacy of a school-based body image intervention in urban India: A pilot randomised controlled trial (2021)
Journal Article

This pilot study evaluated the acceptability and preliminary efficacy of a culturally adapted school-based body image intervention, Dove Confident Me, for use in urban India. Two private schools in New Delhi were randomly assigned at the school level... Read More about Acceptability and preliminary efficacy of a school-based body image intervention in urban India: A pilot randomised controlled trial.

Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma (2021)
Journal Article

Introduction. Glioblastoma (GBM) is the most common primary adult brain tumour with a median overall survival (OS) of 12-15 months. Molecular characterization of multiple immunooncology targets in GBM may help target novel immunotherapeutic strategie... Read More about Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma.

A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder (2021)
Journal Article

Introduction: Neoadjuvant cisplatin-based combination chemotherapy improves survival in muscle-invasive bladder cancer. However, response rates and survival remain suboptimal. We evaluated the efficacy, safety, and tolerability of cisplatin plus caba... Read More about A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder.

Fixed bearing, all-polyethylene tibia, lateral unicompartmental arthroplasty – A final outcome study with up to 28 year follow-up of a single implant (2021)
Journal Article

Background: Lateral unicompartmental arthroplasty (UKA) constitutes only 5–10% of all unicompartmental replacements performed. Whilst the short and medium term benefits are well documented, there remains concern regarding the higher revision rate whe... Read More about Fixed bearing, all-polyethylene tibia, lateral unicompartmental arthroplasty – A final outcome study with up to 28 year follow-up of a single implant.

St Georg Sled medial unicompartmental arthroplasty: survivorship analysis and function at 20years follow up (2021)
Journal Article

Purpose: The peri-operative and short-term benefits of unicompartmental knee arthroplasty (UKA) are well supported in the literature. However, there remains concern regarding the higher revision rate when compared with total knee replacement. This ma... Read More about St Georg Sled medial unicompartmental arthroplasty: survivorship analysis and function at 20years follow up.