All Outputs (108)

An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS (2013)
Journal Article
Ratcliffe, N., De Lacy Costello, B., Al-Kateb, H., de Lacy Costello, B., & Ratcliffe, N. M. (2013). An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS. Journal of Breath Research, 7(3), https://doi.org/10.1088/1752-7155/7/3/036004

Analysis of volatile organic compounds (VOCs) from saliva, to aid disease diagnoses, has received little attention. This work aims to address the paucity of information on saliva volatiles and includes a database of newly identified compounds whilst... Read More about An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS.

The Development of Novel Fuel Dehydrating Icing Inhibitors (2013)
Journal Article
Lam, J. K., de Lacy Costello, B., Repetto, S. L., Repetto, S., Costello, J. F., de Lacy Costello, B., …Lam, J. (2013). The Development of Novel Fuel Dehydrating Icing Inhibitors. SAE International Journal of Fuels and Lubricants, 6(3), 553-563. https://doi.org/10.4271/2013-01-2169

Dissolved water is a normal component of jet fuel which is vapourised during combustion; however, free water is a contaminant that can starve engines, freeze to form ice crystals capable of blocking fuel feeds, support microbial growth, and contribut... Read More about The Development of Novel Fuel Dehydrating Icing Inhibitors.

A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace (2013)
Journal Article
Ratcliffe, N., Probert, C. S., Ewen, R., Khalid, T., White, P., De Lacy Costello, B., …Ratcliffe, N. M. (2013). A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace. PLoS ONE, 8(7), https://doi.org/10.1371/journal.pone.0069602

There is a need to reduce the number of cystoscopies on patients with haematuria. Presently there are no reliable biomarkers to screen for bladder cancer. In this paper, we evaluate a new simple in-house fabricated, GC-sensor device in the diagnosis... Read More about A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace.

Observation, characterization and modeling of memristor current spikes (2013)
Journal Article
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013). Observation, characterization and modeling of memristor current spikes. https://doi.org/10.12785/amis/070418

Memristors have been compared to neurons (usually specifically the synapses) since 1976 but no experimental evidence has been offered for support for this position. Here we highlight that memristors naturally form fast-response, highly reproducible a... Read More about Observation, characterization and modeling of memristor current spikes.

The importance of methane breath testing: A review (2013)
Journal Article
Ratcliffe, N. M., De Lacy Costello, B. P., de Lacy Costello, B., Ledochowski, M., & Ratcliffe, N. M. (2013). The importance of methane breath testing: A review. Journal of Breath Research, 7(2), https://doi.org/10.1088/1752-7155/7/2/024001

Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test is now a well established noninvasive test for assessi... Read More about The importance of methane breath testing: A review.

The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease (2013)
Journal Article
Ratcliffe, N. M., de Lacy Costello, B., & Shepherd, S. (2013). The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease. Clinical laboratory international, 37, 18-20

Currently, the diagnosis of bowel diseases such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) relies on invasive and expensive procedures. Identification of biomarker-based tests to aid diagnosis is an important area of resea... Read More about The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease.

An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome (2013)
Journal Article
Probert, C. S., de Costello, B. L., Ahmed, I., Greenwood, R., de Lacy Costello, B., Ratcliffe, N. M., & Probert, C. (2013). An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome. PLoS ONE, 8(3), https://doi.org/10.1371/journal.pone.0058204

Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to invasive investigations in order to rule out other diseases and reassure their patients. Volatile organic metabolites (VOMs) are emitted from feces; understanding... Read More about An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome.

Volatiles from oral anaerobes confounding breath biomarker discovery (2013)
Journal Article
De Lacy Costello, B., Khalid, T. Y., Ratcliffe, N. M., Khalid, T., Saad, S., Greenman, J., …Ratcliffe, N. M. (2013). Volatiles from oral anaerobes confounding breath biomarker discovery. Journal of Breath Research, 7(1), https://doi.org/10.1088/1752-7155/7/1/017114

The levels of compounds in exhaled mouth air do not necessarily reflect levels in the systemic circulation as bacteria can bio-transform substrates to produce compounds within the mouth. This should be of concern to researchers measuring breath volat... Read More about Volatiles from oral anaerobes confounding breath biomarker discovery.

Evolution of plastic learning in spiking networks via memristive connections (2012)
Journal Article
Howard, G., Howard, D., Gale, E., Bull, L., De Lacy Costello, B., & Adamatzky, A. (2012). Evolution of plastic learning in spiking networks via memristive connections. IEEE Transactions on Evolutionary Computation, 16(5), 711-729. https://doi.org/10.1109/TEVC.2011.2170199

This paper presents a spiking neuroevolutionary system which implements memristors as plastic connections, i.e., whose weights can vary during a trial. The evolutionary design process exploits parameter self-adaptation and variable topologies, allowi... Read More about Evolution of plastic learning in spiking networks via memristive connections.

On architectures of circuits implemented in simulated Belousov-Zhabotinsky droplets (2012)
Journal Article
Adamatzky, A., Holley, J., Dittrich, P., Gorecki, J., De Lacy Costello, B., Zauner, K. P., & Bull, L. (2012). On architectures of circuits implemented in simulated Belousov-Zhabotinsky droplets. BioSystems, 109(1), 72-77. https://doi.org/10.1016/j.biosystems.2011.12.007

When lipid vesicles filled with Belousov-Zhabotinsky (BZ) excitable chemical medium are packed in tight assembles, waves of excitation may travel between the vesicles. When several waves meet in a vesicle some fragments may deflect, others can annihi... Read More about On architectures of circuits implemented in simulated Belousov-Zhabotinsky droplets.

Time-dependent wave selection for information processing in excitable media (2012)
Journal Article
Costello, B. D. L., Stevens, W. M., Adamatzky, A., Jahan, I., & de Lacy Costello, B. (2012). Time-dependent wave selection for information processing in excitable media. Physical Review E, 85(6), https://doi.org/10.1103/PhysRevE.85.066129

We demonstrate an improved technique for implementing logic circuits in light-sensitive chemical excitable media. The technique makes use of the constant-speed propagation of waves along defined channels in an excitable medium based on the Belousov-Z... Read More about Time-dependent wave selection for information processing in excitable media.

Computing with liquid crystal fingers: Models of geometric and logical computation (2011)
Journal Article
Younger, D., Matranga, M. A., Kitson, S., Adamatzky, A., & de Lacy Costello, B. (2011). Computing with liquid crystal fingers: Models of geometric and logical computation. Physical Review E, 84(6), https://doi.org/10.1103/PhysRevE.84.061702

When a voltage is applied across a thin layer of cholesteric liquid crystal, fingers of cholesteric alignment can form and propagate in the layer. In computer simulation, based on experimental laboratory results, we demonstrate that these cholesteric... Read More about Computing with liquid crystal fingers: Models of geometric and logical computation.

Logical and arithmetic circuits in Belousov-Zhabotinsky encapsulated disks (2011)
Journal Article
Holley, J., Jahan, I., De Lacy Costello, B., Bull, L., & Adamatzky, A. (2011). Logical and arithmetic circuits in Belousov-Zhabotinsky encapsulated disks. Physical Review E, 84(5), 056110. https://doi.org/10.1103/PhysRevE.84.056110

Excitation waves on a subexcitable Belousov-Zhabotinsky (BZ) substrate can be manipulated by chemical variations in the substrate and by interactions with other waves. Symbolic assignment and interpretation of wave dynamics can be used to perform log... Read More about Logical and arithmetic circuits in Belousov-Zhabotinsky encapsulated disks.

On computing in fine-grained compartmentalised Belousov-Zhabotinsky medium (2011)
Journal Article
Adamatzky, A., Holley, J., Bull, L., & De Lacy Costello, B. (2011). On computing in fine-grained compartmentalised Belousov-Zhabotinsky medium. Chaos, Solitons and Fractals, 44(10), 779-790. https://doi.org/10.1016/j.chaos.2011.03.010

We introduce results of computer experiments on information processing in a hexagonal array of vesicles filled with Belousov-Zhabotinsky (BZ) solution in a sub-excitable mode. We represent values of Boolean variables by excitation wave-fragments and... Read More about On computing in fine-grained compartmentalised Belousov-Zhabotinsky medium.

Vesicle computers: Approximating a Voronoi diagram using Voronoi automata (2011)
Journal Article
Adamatzky, A., De Lacy Costello, B., Holley, J., Gorecki, J., & Bull, L. (2011). Vesicle computers: Approximating a Voronoi diagram using Voronoi automata. Chaos, Solitons and Fractals, 44(7), 480-489. https://doi.org/10.1016/j.chaos.2011.01.016

Irregular arrangements of vesicles filled with excitable and precipitating chemical systems are imitated by Voronoi automata - finite-state machines defined on a planar Voronoi diagram. Every Voronoi cell takes four states: resting, excited, refracto... Read More about Vesicle computers: Approximating a Voronoi diagram using Voronoi automata.

Towards constructing one-bit binary adder in excitable chemical medium (2011)
Journal Article
de Lacy Costello, B., Adamatzky, A., Jahan, I., & Zhang, L. (2011). Towards constructing one-bit binary adder in excitable chemical medium. Chemical Physics, 381(1-3), 88-99. https://doi.org/10.1016/j.chemphys.2011.01.014

The light-sensitive modification (ruthenium catalysed) of the Belousov-Zhabotinsky reaction exhibits various excitability regimes depending on the level of illumination. Within a narrow range of applied illumination levels the medium is in a sub-exci... Read More about Towards constructing one-bit binary adder in excitable chemical medium.

Computational modalities of Belousov-Zhabotinsky encapsulated vesicles (2011)
Journal Article
Holley, J., Adamatzky, A., Bull, L., De Lacy Costello, B., & Jahan, I. (2011). Computational modalities of Belousov-Zhabotinsky encapsulated vesicles. Nano Communication Networks, 2(1), 50-61. https://doi.org/10.1016/j.nancom.2011.02.002

We present both simulated and partial empirical evidences for the computational utility of many connected vesicle analogues of an encapsulated nonlinear chemical processing medium. By connecting small vesicles containing a solution of sub-excitable B... Read More about Computational modalities of Belousov-Zhabotinsky encapsulated vesicles.

Towards arithmetic circuits in sub-excitable chemical media (2011)
Journal Article
Adamatzky, A., De Lacy Costello, B., Bull, L., & Holley, J. (2011). Towards arithmetic circuits in sub-excitable chemical media. Israel Journal of Chemistry, 51(1), 56-66. https://doi.org/10.1002/ijch.201000046

A sub-excitable Belousov-Zhabotinsky medium exhibits localized travelling excitations (in contrast to an excitable medium exhibiting target or spiral waves). Initially assymetric perturbations give birth to excitation wave-fragments. The shape and ve... Read More about Towards arithmetic circuits in sub-excitable chemical media.

On polymorphic logical gates in subexcitable chemical medium (2011)
Journal Article
Adamatzky, A., De Lacy Costello, B., & Bull, L. (2011). On polymorphic logical gates in subexcitable chemical medium. International Journal of Bifurcation and Chaos, 21(07), 1977-1986. https://doi.org/10.1142/S0218127411029574

In a subexcitable light-sensitive Belousov-Zhabotinsky (BZ) chemical medium an asymmetric disturbance causes the formation of localized traveling wave-fragments. Under the right conditions these wave-fragments can conserve their shape and velocity ve... Read More about On polymorphic logical gates in subexcitable chemical medium.

On the internalisation, intraplasmodial carriage and excretion of metallic nanoparticles in the slime mould, Physarum polycephalum (2011)
Journal Article
Mayne, R., Patton, D., Costello, B. D. L., Adamatzky, A., & Patton, R. C. (2011). On the internalisation, intraplasmodial carriage and excretion of metallic nanoparticles in the slime mould, Physarum polycephalum. International Journal of Nanotechnology and Molecular Computation, 3(3), 1-14. https://doi.org/10.4018/ijnmc.2011070101

The plasmodium of Physarum polycephalum is a large single cell visible with the naked eye. When inoculated on a substrate with attractants and repellents the plasmodium develops optimal networks of protoplasmic tubes which span sites of attractants (... Read More about On the internalisation, intraplasmodial carriage and excretion of metallic nanoparticles in the slime mould, Physarum polycephalum.