A systematic investigation of the effect of sample diluent on peak shape in hydrophilic interaction liquid chromatography

Ruta, Josephine; Rudaz, Serge; McCalley, David V.; Veuthey, Jean Luc; Guillarme, Davy

Abstract

The aim of this study was to evaluate the importance of sample diluents to improve peak shapes in hydrophilic interaction liquid chromatography (HILIC), using low molecular weight (

Citation

Ruta, J., Rudaz, S., McCalley, D. V., Veuthey, J. L., & Guillarme, D. (2010). A systematic investigation of the effect of sample diluent on peak shape in hydrophilic interaction liquid chromatography. Journal of Chromatography A, 1217(52), 8230-8240. https://doi.org/10.1016/j.chroma.2010.10.106

• Journal Article Type: Article
• Publication Date: Dec 24, 2010
• Journal: Journal of Chromatography A
• Print ISSN: 0021-9673
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 1217
• Issue: 52
• Pages: 8230-8240
• DOI: https://doi.org/10.1016/j.chroma.2010.10.106
• Keywords: HILIC, dissolution solvent, sample diluent, peptides, small compounds, UHPLC
• Public URL: https://uwe-repository.worktribe.com/output/972669
• Publisher URL: http://dx.doi.org/10.1016/j.chroma.2010.10.106