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A systematic investigation of the effect of sample diluent on peak shape in hydrophilic interaction liquid chromatography

Ruta, Josephine; Rudaz, Serge; McCalley, David V.; Veuthey, Jean Luc; Guillarme, Davy

Authors

Josephine Ruta

Serge Rudaz

Jean Luc Veuthey

Davy Guillarme



Abstract

The aim of this study was to evaluate the importance of sample diluents to improve peak shapes in hydrophilic interaction liquid chromatography (HILIC), using low molecular weight (

Journal Article Type Article
Publication Date Dec 24, 2010
Journal Journal of Chromatography A
Print ISSN 0021-9673
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 1217
Issue 52
Pages 8230-8240
DOI https://doi.org/10.1016/j.chroma.2010.10.106
Keywords HILIC, dissolution solvent, sample diluent, peptides, small compounds, UHPLC
Public URL https://uwe-repository.worktribe.com/output/972669
Publisher URL http://dx.doi.org/10.1016/j.chroma.2010.10.106