Maternal dietary patterns during pregnancy and intelligence quotients in the offspring at 8years of age: Findings from the ALSPAC cohort

Freitas Vilela, Ana Am�lia; Pearson, Rebecca M; Emmett, Pauline; Heron, Jon; Smith, Andrew D A C; Emond, Alan; Hibbeln, Joseph R; Trindade Castro, Maria Beatriz; Kac, Gilberto

Abstract

© 2017 The Authors. Maternal & Child Nutrition Published by John Wiley & Sons Ltd Dietary intake during pregnancy may influence child neurodevelopment and cognitive function. This study aims to investigate the associations between dietary patterns obtained in pregnancy and intelligence quotients (IQ) among offspring at 8years of age. Pregnant women enrolled in the Avon Longitudinal Study of Parents and Children completed a food frequency questionnaire at 32weeks' gestation (n=12,195). Dietary patterns were obtained by cluster analysis. Three clusters best described women's diets during pregnancy: “fruit and vegetables,” “meat and potatoes,” and “white bread and coffee.” The offspring's IQ at 8years of age was assessed using the Wechsler Intelligence Scale for Children. Models, using variables correlated to IQ data, were performed to impute missing values. Linear regression models were employed to investigate associations between the maternal clusters and IQ in childhood. Children of women who were classified in the meat and potatoes cluster and white bread and coffee cluster during pregnancy had lower average verbal (β=−1.74; p

• Journal Article Type: Article
• Acceptance Date: Jan 9, 2017
• Online Publication Date: Mar 2, 2017
• Publication Date: Jan 1, 2018
• Deposit Date: Mar 10, 2017
• Publicly Available Date: Mar 10, 2017
• Journal: Maternal and Child Nutrition
• Print ISSN: 1740-8709
• Electronic ISSN: 1740-8709
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 14
• Issue: 1
• Pages: e12431
• DOI: https://doi.org/10.1111/mcn.12431
• Keywords: ALSPAC, children, cluster analysis, dietary patterns, intelligence quotient, pregnancy
• Public URL: https://uwe-repository.worktribe.com/output/871837
• Publisher URL: http://dx.doi.org/10.1111/mcn.12431
• Contract Date: Mar 10, 2017