The research focuses on how to make urban and rural settlements greener, healthier and more resilient. The increase in the global population combined with massive urbanisation is increasing need for risk resilience from disasters, particularly in coastal and fluvial areas. This research explores how development can mitigate, respond, recover and adapt to disasters particularly in light of climate change and in line with the 2015 Sendai Framework for Disaster Risk Reduction. It is important to develop strategies in relation to specific local social and cultural contexts. This approach to research is particularly focused on working collaboratively and inter-disciplinary, particularly for complex socio-natural issues. As Brazil faces huge inequalities in health it requires radical approaches to develop appropriate local strategies for improving resilience in coastal and river areas. The aim of the research is to co-design knowledge to promote resilient, safe and vibrant communities.