Challenges and opportunities for involving patients and the public in acute antimicrobial medicine development research: An interview study

Gibson, Andy; Kok, Michele; Evans, David; Grier, Sally; Macgowan, Alasdair

Abstract

Objectives: To explore what approaches to patient and public involvement (PPI) in antimicrobial medicines development are currently being utilised, what are the impacts of PPI on antimicrobial medicines development and what are the barriers to its implementation?

Design: Interview study.

Setting: Antimicrobial medicines development research.

Participants: Principal investigators known to have led studies involving PPI or expressed an interest in PPI.

Results: There is very little published work PPI in antimicrobial research. Individual interviewees expressed scepticism about the contribution that PPI could make to different stages of the medicines development life cycle but collectively identified a range of potential benefits of PPI covering most stages of the medicines development process.

Conclusions: A major issue in developing PPI in antimicrobial medicines development research will be in overcoming the view that, at best, PPI has only a marginal contribution to make in this area of research. The findings from this study, although mixed, suggest that well designed PPI has an untapped potential to enhance antimicrobial research.

• Journal Article Type: Article
• Acceptance Date: Oct 17, 2018
• Online Publication Date: May 1, 2019
• Publication Date: May 1, 2019
• Deposit Date: Jan 11, 2019
• Publicly Available Date: Jan 11, 2019
• Journal: BMJ Open
• Electronic ISSN: 2044-6055
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 9
• Issue: 4
• DOI: https://doi.org/10.1136/bmjopen-2018-024918
• Keywords: antimicrobial research, patient and public involvement, challenges and opportunities, acute infections
• Public URL: https://uwe-repository.worktribe.com/output/858555
• Publisher URL: https://onlinelibrary.wiley.com/journal/13697625
• Contract Date: Jan 11, 2019