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Randomised trial of the fascia iliaca block versus the '3-in-1' block for femoral neck fractures in the emergency department

Smith, Jason E.; Reavley, Paul; Montgomery, Alan A.; Smith, Jason E; Binks, Simon; Edwards, Judith; Elder, Georgina; Benger, Jonathan


Jason E. Smith

Paul Reavley

Alan A. Montgomery

Jason E Smith

Simon Binks

Judith Edwards

Georgina Elder

Jonathan Benger


Introduction Femoral neck fractures are a common and painful injury. Femoral nerve blocks, and a variant of this technique termed the '3-in-1' block, are often used in this patient group, but their effect is variable. The fascia iliaca compartment block (FIB) has been proposed as an alternative, but the relative effectiveness of the two techniques in the early stages of care is unknown. We therefore compared the FIB versus the 3-in-1 block in a randomised trial conducted in two UK emergency departments. Methods Parallel, two-group randomised equivalence trial. Consenting patients >18 years with a femoral neck fracture were randomly allocated to receive either a FIB or a 3-in-1 block. The primary outcome was pain measured on a 100 mm visual analogue scale at 60 min. The between-group difference was adjusted for centre, age, sex, fracture type, pre-block analgesia and pre-block pain score. Results 178 patients were randomised and 162 included in the primary analysis. The mean 100 mm visual analogue pain scale score at 60 min was 38 mm in the FIB arm and 35 mm in the 3-in-1 arm. The adjusted difference between the arms was 3 mm, with a 95%CI (-4.7 to 10.8) that excluded a clinically important difference between the two interventions. Conclusions FIB is equivalent to the 3-in-1 block for immediate pain relief in adult neck of femur fractures. Trial registration number ISRCTN16152419.


Smith, J. E., Reavley, P., Montgomery, A. A., Smith, J. E., Binks, S., Edwards, J., …Benger, J. (2015). Randomised trial of the fascia iliaca block versus the '3-in-1' block for femoral neck fractures in the emergency department. Emergency Medicine Journal, 32(9), 685-689.

Journal Article Type Article
Publication Date Jan 1, 2015
Journal Emergency Medicine Journal
Print ISSN 1472-0205
Electronic ISSN 1472-0213
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Volume 32
Issue 9
Pages 685-689
Keywords femoral neck fractures, emergency medicine
Public URL
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