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Phase II pragmatic randomized controlled trial of patient-led therapies (Mirror Therapy and Lower-Limb Exercises) during inpatient stroke rehabilitation

Tyson, Sarah; Wilkinson, Jack; Thomas, Nessa; Selles, Ruud; McCabe, Candy; Tyrrell, Pippa; Vail, Andy

Phase II pragmatic randomized controlled trial of patient-led therapies (Mirror Therapy and Lower-Limb Exercises) during inpatient stroke rehabilitation Thumbnail


Authors

Sarah Tyson

Jack Wilkinson

Nessa Thomas

Ruud Selles

Candy McCabe Candy.Mccabe@uwe.ac.uk
Florence Nightingale Foundation Chair

Pippa Tyrrell

Andy Vail



Abstract

© American Society of Neurorehabilitation. Background and objective. Patient-led therapy has the potential to increase the amount of therapy patients undertake during stroke rehabilitation and to enhance recovery. Our objective was to assess the feasibility and acceptability of 2 patient-led therapies during the acute stages of stroke care: mirror therapy for the upper limb and lower-limb exercises for the lower limb. Methods. This was a blind assessed, multicenter, pragmatic randomized controlled trial of patient-led upper-limb mirror therapy and patient-led lower leg exercises. Stroke survivors with upper and lower limb limitations, undergoing inpatient rehabilitation and able to consent were recruited at least 1 week poststroke. Results. Both interventions proved feasible, with >90% retention. No serious adverse events were reported. Both groups did less therapy than recommended; typically 5 to 15 minutes for 7 days or less. Participants receiving mirror therapy (n = 63) tended to do less practice than those doing lower-limb exercises (n = 31). Those with neglect did 69% less mirror therapy than those without (P =.02), which was not observed in the exercise group. Observed between-group differences were modest but neglect, upper-limb strength, and dexterity showed some improvement in the mirror therapy group. No changes were seen in the lower-limb group. Conclusions. Both patient-led mirror therapy and lower-limb exercises during inpatient stroke care are safe, feasible, and acceptable and warrant further investigation. Practice for 5 to 15 minutes for 7 days is a realistic prescription unless strategies to enhance adherence are included.

Journal Article Type Article
Publication Date Jan 1, 2015
Journal Neurorehabilitation and Neural Repair
Print ISSN 1545-9683
Electronic ISSN 1552-6844
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 29
Issue 9
Pages 818-826
Institution Citation Tyson, S., Wilkinson, J., Thomas, N., Selles, R., McCabe, C., Tyrrell, P., & Vail, A. (2015). Phase II pragmatic randomized controlled trial of patient-led therapies (Mirror Therapy and Lower-Limb Exercises) during inpatient stroke rehabilitation. Neurorehabilitation and Neural Repair, 29(9), 818-826. https://doi.org/10.1177/1545968314565513
DOI https://doi.org/10.1177/1545968314565513
Keywords stroke, patient-led, mirror therapy, exercise
Publisher URL http://dx.doi.org/10.1177/1545968314565513

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