Bethany Little
Language in schizophrenia and aphasia: The relationship with non-verbal cognition and thought disorder
Little, Bethany; Gallagher, Peter; Zimmerer, Vitor; Varley, Rosemary; Douglas, Maggie; Spencer, Helen; �okal, Derya; Deamer, Felicity; Turkington, Douglas; Ferrier, I. Nicol; Hinzen, Wolfram; Watson, Stuart
Authors
Peter Gallagher
Vitor Zimmerer
Rosemary Varley
Maggie Douglas
Helen Spencer
Derya �okal
Dr Felicity Deamer Felicity.Deamer@uwe.ac.uk
Douglas Turkington
I. Nicol Ferrier
Wolfram Hinzen
Stuart Watson
Abstract
Objective: To determine the relationship between language abnormalities and broader cognitive impairment and thought disorder by examining language and cognition in schizophrenia and aphasia (a primary language disorder). Methods: Cognitive and linguistic profiles were measured with a battery of standardised tests, and compared in a clinical population of n = 50 (n = 30 with schizophrenia and n = 20 with aphasia) and n = 61 non-clinical comparisons (n = 45 healthy controls and n = 16 non-affected first-degree relatives of patients with schizophrenia). Results: Both clinical groups showed linguistic deficits. Verbal impairment was more severe in participants with aphasia, whereas non-verbal performance was more affected in participants with schizophrenia. In schizophrenia, but not in aphasia, verbal and non-verbal performance were associated. Formal thought disorder was associated with impairment in executive function and in grammatical, but not naming, tasks. Conclusion: While patients with schizophrenia and aphasia showed language impairments, the nature and cognitive basis of these impairments may be different; language performance disassociates from broader cognitive functioning in aphasia but may be an intrinsic expression of a broader cognitive impairment in schizophrenia. Thought disorder may represent a core malfunction of grammatical processing. Results suggests that communicative ability may be a valid target in cognitive remediation strategies in schizophrenia.
Citation
Little, B., Gallagher, P., Zimmerer, V., Varley, R., Douglas, M., Spencer, H., …Watson, S. (2019). Language in schizophrenia and aphasia: The relationship with non-verbal cognition and thought disorder. Cognitive Neuropsychiatry, 24(6), 389-405. https://doi.org/10.1080/13546805.2019.1668758
Journal Article Type | Article |
---|---|
Acceptance Date | Oct 21, 2019 |
Online Publication Date | Sep 25, 2019 |
Publication Date | Nov 2, 2019 |
Deposit Date | Sep 21, 2021 |
Journal | Cognitive Neuropsychiatry |
Print ISSN | 1354-6805 |
Electronic ISSN | 1464-0619 |
Publisher | Taylor & Francis (Routledge) |
Peer Reviewed | Peer Reviewed |
Volume | 24 |
Issue | 6 |
Pages | 389-405 |
DOI | https://doi.org/10.1080/13546805.2019.1668758 |
Keywords | Psychiatry and Mental health; Cognitive Neuroscience |
Public URL | https://uwe-repository.worktribe.com/output/7816038 |
Additional Information | Peer Review Statement: The publishing and review policy for this title is described in its Aims & Scope.; Aim & Scope: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=pcnp20; Received: 2018-05-31; Accepted: 2019-09-04; Published: 2019-09-25 |
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