Alex Yue Alex.Yue@uwe.ac.uk
Senior Lecturer in Bioinstrumentation and Sensor Interfacing
Generation of spatio-temporal concentration profiles for cell culture systems: A case study in ammonia
Yue, Xicai; Drakakisa, Emmanuel M.; Mantalaris, Athanasios; Cass, Anthony
Authors
Emmanuel M. Drakakisa
Athanasios Mantalaris
Anthony Cass
Abstract
Cellular behavior is influenced by micro-concentration gradients existing in their immediate spatio-environment. A practical real-time measurement system, composed of miniaturized long-lasting sensors placed within a two-dimensional bioreactor and a 32-channel data acquisition system for ammonia, is presented in this paper aiming to generate the spatio-temporal ammonia concentration profiles for the whole culture process. Our results demonstrate the feasibility of the system and its applicability in elucidating the cell growth micro-environment within a bioreactor, which can potentially facilitate the intelligent control of ammonia levels in cell culture systems. The presented system is flexible enough to interface other sensors for generating their spatio-temporal profiles of the sensed cell culture
parameters.
Citation
Yue, X., Drakakisa, E. M., Mantalaris, A., & Cass, A. (2010). Generation of spatio-temporal concentration profiles for cell culture systems: A case study in ammonia. Measurement, 43(9), 1207-1216. https://doi.org/10.1016/j.measurement.2010.05.012
Journal Article Type | Article |
---|---|
Online Publication Date | Jun 10, 2010 |
Publication Date | Nov 1, 2010 |
Deposit Date | May 7, 2021 |
Print ISSN | 1536-6367 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 43 |
Issue | 9 |
Pages | 1207-1216 |
DOI | https://doi.org/10.1016/j.measurement.2010.05.012 |
Public URL | https://uwe-repository.worktribe.com/output/5667469 |
You might also like
Speed settling of AC-coupled amplifier for active contactless ECG electrode
(2023)
Conference Proceeding
Disturbance-observer-based u-control (Dobuc) for nonlinear dynamic systems
(2021)
Journal Article
Downloadable Citations
About UWE Bristol Research Repository
Administrator e-mail: repository@uwe.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search