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Light-induced spiking in proteinoids yields Boolean gates

Mougkogiannis, Panagiotis; Adamatzky, Andrew


Panagiotis Mougkogiannis


This study analyzes light modulation of spiking in proteinoids, thermally condensed proteins exhibiting spike dynamics. We elucidate how light induces changes in proteinoids, modulating spike frequency. Results show proteinoids' spiking can be adjusted by light intensity and wavelength. Structural investigations demonstrate light triggers conformational changes influencing spiking kinetics. Spiking proteinoids can perform Boolean logic, generating programmable expressions in response to light input modifications. This reveals potential unconventional computing applications. Our comprehensive analyses establish a fundamental understanding of light's impact on proteinoids' structure and protrusion dynamics, facilitating optically programmed bio-logic gates. Outcomes will catalyze future research into light-modified proteinoids for information processing and unconventional computation. In summary, this study provides key insights into light modulation of proteinoids' spiking behavior, enabling novel optically controlled bio-logic gate operations and motivating continued efforts to integrate photo-responsive proteinoids in bioinspired computational systems.


Mougkogiannis, P., & Adamatzky, A. (in press). Light-induced spiking in proteinoids yields Boolean gates. Materials and Design,

Journal Article Type Article
Acceptance Date Nov 5, 2023
Online Publication Date Nov 14, 2023
Deposit Date Nov 15, 2023
Journal Materials and Design
Print ISSN 0264-1275
Publisher Elsevier
Peer Reviewed Peer Reviewed
Keywords thermal proteins; proteinoids; microspheres; unconventional computing
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